Andrew D. Piekarz, Ph.D.

Affiliations: 
2012 Pharmacology and Toxicology Indiana University, Bloomington, Bloomington, IN, United States 
Area:
Ion channel physiology and pharmacology, pain, neurophysiology
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"Andrew Piekarz"
Mean distance: 15.74 (cluster 11)
 
SNBCP

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Theodore R. Cummins grad student 2012 Indiana University
 (Increased resurgent sodium currents (INaR) in inherited and acquired disorders of excitability.)
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Publications

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Tan ZY, Piekarz AD, Priest BT, et al. (2014) Tetrodotoxin-resistant sodium channels in sensory neurons generate slow resurgent currents that are enhanced by inflammatory mediators. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 34: 7190-7
King AM, Yang XF, Wang Y, et al. (2012) Identification of the benzyloxyphenyl pharmacophore: a structural unit that promotes sodium channel slow inactivation. Acs Chemical Neuroscience. 3: 1037-49
Due MR, Piekarz AD, Wilson N, et al. (2012) Neuroexcitatory effects of morphine-3-glucuronide are dependent on Toll-like receptor 4 signaling. Journal of Neuroinflammation. 9: 200
Piekarz AD, Due MR, Khanna M, et al. (2012) CRMP-2 peptide mediated decrease of high and low voltage-activated calcium channels, attenuation of nociceptor excitability, and anti-nociception in a model of AIDS therapy-induced painful peripheral neuropathy. Molecular Pain. 8: 54
Song W, Xiao Y, Chen H, et al. (2012) The human Nav1.5 F1486 deletion associated with long QT syndrome leads to impaired sodium channel inactivation and reduced lidocaine sensitivity. The Journal of Physiology. 590: 5123-39
Wilson SM, Brittain JM, Piekarz AD, et al. (2011) Further insights into the antinociceptive potential of a peptide disrupting the N-type calcium channel-CRMP-2 signaling complex. Channels (Austin, Tex.). 5: 449-56
Theile JW, Jarecki BW, Piekarz AD, et al. (2011) Nav1.7 mutations associated with paroxysmal extreme pain disorder, but not erythromelalgia, enhance Navbeta4 peptide-mediated resurgent sodium currents. The Journal of Physiology. 589: 597-608
Jarecki BW, Piekarz AD, Jackson JO, et al. (2010) Human voltage-gated sodium channel mutations that cause inherited neuronal and muscle channelopathies increase resurgent sodium currents. The Journal of Clinical Investigation. 120: 369-78
Brittain JM, Piekarz AD, Wang Y, et al. (2009) An atypical role for collapsin response mediator protein 2 (CRMP-2) in neurotransmitter release via interaction with presynaptic voltage-gated calcium channels. The Journal of Biological Chemistry. 284: 31375-90
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