Hannah A. Hathaway, Ph.D.

Affiliations: 
2014 Pharmacology Georgetown University, Washington, DC 
Area:
Neuropharmacology, glutamate receptors
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"Hannah Hathaway"
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Parents

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Jarda T. Wroblewski grad student 2014 Georgetown
 (Function and signal transduction of metabotropic glutamate receptor 1 in cerebellar granule cells.)
Wendy B. Macklin post-doc University of Colorado, Denver
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Publications

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Dahl KD, Almeida AR, Hathaway HA, et al. (2022) mTORC2 loss in oligodendrocyte progenitor cells results in regional hypomyelination in the central nervous system. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience
Kohnke S, Buller S, Nuzzaci D, et al. (2021) Nutritional regulation of oligodendrocyte differentiation regulates perineuronal net remodeling in the median eminence. Cell Reports. 36: 109362
Gelb T, Pshenichkin S, Hathaway HA, et al. (2015) Atypical signaling of metabotropic glutamate receptor 1 in human melanoma cells. Biochemical Pharmacology. 98: 182-9
Hathaway HA, Pshenichkin S, Grajkowska E, et al. (2015) Pharmacological characterization of mGlu1 receptors in cerebellar granule cells reveals biased agonism. Neuropharmacology. 93: 199-208
Gelb T, Pshenichkin S, Rodriguez OC, et al. (2015) Metabotropic glutamate receptor 1 acts as a dependence receptor creating a requirement for glutamate to sustain the viability and growth of human melanomas. Oncogene. 34: 2711-20
Gelb T, Pshenichkin S, Hathaway HA, et al. (2015) Abstract A15: mGlu1 Receptors and downstream signal transduction proteins as therapeutic targets for the treatment of metastatic melanoma Cancer Research. 75
Gelb T, Hathaway HA, Wroblewski JT. (2014) Triple threat treatment: Exploiting the dependence receptor properties of metabotropic glutamate receptor 1 against melanoma. Molecular & Cellular Oncology. 1: e969163
DiRaddo JO, Miller EJ, Hathaway HA, et al. (2014) A real-time method for measuring cAMP production modulated by Gαi/o-coupled metabotropic glutamate receptors. The Journal of Pharmacology and Experimental Therapeutics. 349: 373-82
Emery AC, DiRaddo JO, Miller E, et al. (2012) Ligand bias at metabotropic glutamate 1a receptors: molecular determinants that distinguish β-arrestin-mediated from G protein-mediated signaling. Molecular Pharmacology. 82: 291-301
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