Matthew R. Fleming, Ph.D.

Affiliations: 
2012 Yale University, New Haven, CT 
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"Matthew Fleming"
Mean distance: 14.94 (cluster 6)
 

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Leonard K. Kaczmarek grad student 2012 Yale
 (Phosphorylation regulates gating and channel-protein interactions in the Slack sodium-activated potassium channel.)
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Publications

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Fleming MR, Brown MR, Kronengold J, et al. (2016) Stimulation of Slack K(+) Channels Alters Mass at the Plasma Membrane by Triggering Dissociation of a Phosphatase-Regulatory Complex. Cell Reports
Zhang Y, Zhang XF, Fleming MR, et al. (2016) Kv3.3 Channels Bind Hax-1 and Arp2/3 to Assemble a Stable Local Actin Network that Regulates Channel Gating. Cell
Fleming MR, Shamah SM, Kaczmarek LK. (2014) Use of label-free optical biosensors to detect modulation of potassium channels by G-protein coupled receptors. Journal of Visualized Experiments : Jove. e51307
Martin HC, Kim GE, Pagnamenta AT, et al. (2014) Clinical whole-genome sequencing in severe early-onset epilepsy reveals new genes and improves molecular diagnosis. Human Molecular Genetics. 23: 3200-11
Zhang Y, Brown MR, Hyland C, et al. (2012) Regulation of neuronal excitability by interaction of fragile X mental retardation protein with slack potassium channels. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 15318-27
Barcia G, Fleming MR, Deligniere A, et al. (2012) De novo gain-of-function KCNT1 channel mutations cause malignant migrating partial seizures of infancy. Nature Genetics. 44: 1255-9
Fleming MR, Kaczmarek LK. (2009) Use of optical biosensors to detect modulation of Slack potassium channels by G protein-coupled receptors. Journal of Receptor and Signal Transduction Research. 29: 173-81
Schmidt JT, Fleming MR, Leu B. (2004) Presynaptic protein kinase C controls maturation and branch dynamics of developing retinotectal arbors: possible role in activity-driven sharpening. Journal of Neurobiology. 58: 328-40
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