Ian W. Glaaser, Ph.D.

Affiliations: 
2010 Columbia University, New York, NY 
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"Ian Glaaser"
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SNBCP

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Robert S. Kass grad student 2010 Columbia
 (Structural basis of cardiac voltage-gated sodium channel inactivation.)
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Publications

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Mathiharan YK, Glaaser IW, Zhao Y, et al. (2021) Structural insights into GIRK2 channel modulation by cholesterol and PIP. Cell Reports. 36: 109619
Zhao Y, Gameiro-Ros I, Glaaser IW, et al. (2021) Advances in Targeting GIRK Channels in Disease. Trends in Pharmacological Sciences. 42: 203-215
Zhao Y, Ung PM, Zahoránszky-Kőhalmi G, et al. (2020) Identification of a G-Protein-Independent Activator of GIRK Channels. Cell Reports. 31: 107770
Glaaser IW, Mathiharan YK, Zhao Y, et al. (2020) CRYO-EM Structures of the GIRK2 Channel Reveal Mechanisms for Lipid Modulation Biophysical Journal. 118: 497a-498a
Lacin E, Aryal P, Glaaser IW, et al. (2017) Dynamic role of the tether helix in PIP2-dependent gating of a G protein-gated potassium channel. The Journal of General Physiology
Glaaser IW, Slesinger PA. (2017) Dual activation of neuronal G protein-gated inwardly rectifying potassium (GIRK) channels by cholesterol and alcohol. Scientific Reports. 7: 4592
Glaaser IW, Slesinger PA. (2017) Small Molecule Modulation of Brain GIRK Channels Biophysical Journal. 112: 182a-183a
Glaaser IW, Slesinger PA. (2015) Structural Insights into GIRK Channel Function. International Review of Neurobiology. 123: 117-60
Glaaser IW, Marsh NO, Choe S, et al. (2015) Alcohol Inhibition of a Chemically-Activated GIRK2 Channel Biophysical Journal. 108: 367a
Glaaser IW, Osteen JD, Puckerin A, et al. (2012) Perturbation of sodium channel structure by an inherited Long QT Syndrome mutation. Nature Communications. 3: 706
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