Florian T. Merkle, Ph.D.

Affiliations: 
2007 Neuroscience University of California, San Francisco, San Francisco, CA 
Area:
Neural stem cells
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"Florian Merkle"
Mean distance: 15.46 (cluster 6)
 
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Arturo Alvarez-Buylla grad student 2007 UCSF
 (The lineage and diversity of postnatal neural stem cells.)
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Publications

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Burberry A, Suzuki N, Wang JY, et al. (2016) Loss-of-function mutations in the C9ORF72 mouse ortholog cause fatal autoimmune disease. Science Translational Medicine. 8: 347ra93
Merkle FT, Neuhausser WM, Santos D, et al. (2015) Efficient CRISPR-Cas9-Mediated Generation of Knockin Human Pluripotent Stem Cells Lacking Undesired Mutations at the Targeted Locus. Cell Reports. 11: 875-83
Liu J, Merkle FT, Gandhi AV, et al. (2015) Evolutionarily conserved regulation of hypocretin neuron specification by Lhx9. Development (Cambridge, England). 142: 1113-24
Merkle FT, Maroof A, Wataya T, et al. (2015) Generation of neuropeptidergic hypothalamic neurons from human pluripotent stem cells. Development (Cambridge, England). 142: 633-43
Kiskinis E, Sandoe J, Williams LA, et al. (2014) Pathways disrupted in human ALS motor neurons identified through genetic correction of mutant SOD1. Cell Stem Cell. 14: 781-95
Merkle FT, Fuentealba LC, Sanders TA, et al. (2014) Adult neural stem cells in distinct microdomains generate previously unknown interneuron types. Nature Neuroscience. 17: 207-14
Suzuki N, Maroof AM, Merkle FT, et al. (2013) The mouse C9ORF72 ortholog is enriched in neurons known to degenerate in ALS and FTD. Nature Neuroscience. 16: 1725-7
Merkle FT, Eggan K. (2013) Modeling human disease with pluripotent stem cells: from genome association to function. Cell Stem Cell. 12: 656-68
Maroof AM, Keros S, Tyson JA, et al. (2013) Directed differentiation and functional maturation of cortical interneurons from human embryonic stem cells. Cell Stem Cell. 12: 559-72
Alvarez-Buylla A, Merkle F, Fuentealba L. (2013) Neurogenesis in the Postnatal VZ-SVZ and the Origin of Interneuron Diversity Comprehensive Developmental Neuroscience: Patterning and Cell Type Specification in the Developing Cns and Pns. 537-550
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