Amber L. Southwell, Ph.D.

Affiliations: 
2017- Burnett School of Biomedical Sciences-Neuroscience University of Central Florida, Orlando, FL, United States 
Area:
Huntington disease, experimental therapeutics, transgenic mice, behavior, stem cells
Website:
https://med.ucf.edu/biomed/directory/dr-amber-southwell/
Google:
"Amber Southwell"
Mean distance: 14.39 (cluster 11)
 
SNBCP

Parents

Sign in to add mentor
David J. Anderson grad student 2001
Erin M. Schuman grad student 2002
Henry A. Lester grad student 2003
Paul H. Patterson grad student 2009 Caltech
 (Intrabodies as Therapeutics for Huntington's Disease.)
Michael R. Hayden post-doc 2009-2016 UBC
 (Huntington disease therapeutics)
BETA: Related publications

Publications

You can help our author matching system! If you notice any publications incorrectly attributed to this author, please sign in and mark matches as correct or incorrect.

Machiela E, Southwell AL. (2020) Biological Aging and the Cellular Pathogenesis of Huntington's Disease. Journal of Huntington's Disease
Bartl S, Oueslati A, Southwell AL, et al. (2020) Inhibiting cellular uptake of mutant huntingtin using a monoclonal antibody: Implications for the treatment of Huntington's disease. Neurobiology of Disease. 104943
Caron NS, Southwell AL, Brouwers CC, et al. (2019) Potent and sustained huntingtin lowering via AAV5 encoding miRNA preserves striatal volume and cognitive function in a humanized mouse model of Huntington disease. Nucleic Acids Research
Southwell AL, Kordasiewicz HB, Langbehn D, et al. (2018) Huntingtin suppression restores cognitive function in a mouse model of Huntington's disease. Science Translational Medicine. 10
Ehrnhoefer DE, Martin DDO, Schmidt ME, et al. (2018) Preventing mutant huntingtin proteolysis and intermittent fasting promote autophagy in models of Huntington disease. Acta Neuropathologica Communications. 6: 16
Ehrnhoefer DE, Southwell AL, Sivasubramanian M, et al. (2017) HACE1 is essential for astrocyte mitochondrial function and influences Huntington disease phenotypes in vivo. Human Molecular Genetics
Southwell AL, Skotte NH, Villanueva EB, et al. (2017) A novel humanized mouse model of Huntington disease for preclinical development of therapeutics targeting mutant huntingtin alleles. Human Molecular Genetics
Sanders SS, Parsons MP, Mui KK, et al. (2016) Sudden death due to paralysis and synaptic and behavioral deficits when Hip14/Zdhhc17 is deleted in adult mice. Bmc Biology. 14: 108
Southwell AL, Smith-Dijak A, Kay C, et al. (2016) An enhanced Q175 knock-in mouse model of Huntington disease with higher mutant huntingtin levels and accelerated disease phenotypes. Human Molecular Genetics
Connolly C, Magnusson-Lind A, Lu G, et al. (2016) Enhanced Immune Response to MMP3 stimulation in Microglia Expressing Mutant Huntingtin. Neuroscience
See more...