Thomas J. Klein, Ph.D.
Affiliations: | 2006 | Icahn School of Medicine at Mount Sinai, New York, NY, United States |
Area:
Developmental genetics/drosophila retina/planar polarityGoogle:
"Thomas Klein"Mean distance: 16.89 (cluster 6) | S | N | B | C | P |
Parents
Sign in to add mentor| Marek Mlodzik | grad student | 2006 | Mount Sinai School of Medicine | |
| (Molecular mechanisms regulating Frizzled receptor signal specificity.) | ||||
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Publications
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| Kalodimou K, Stapountzi M, Vüllings N, et al. (2023) Separable Roles for Neur and Ubiquitin in Delta Signalling in the CNS Lineages. Cells. 12 |
| Reiff T, Baeumers M, Tibbe C, et al. (2021) Unravelling of Hidden Secrets: The Tumour Suppressor Lethal (2) Giant Discs (Lgd)/CC2D1, Notch Signalling and Cancer. Advances in Experimental Medicine and Biology. 1287: 31-46 |
| Baeumers M, Ruhnau K, Breuer T, et al. (2020) Lethal (2) giant discs (Lgd)/CC2D1 is required for the full activity of the ESCRT machinery. Bmc Biology. 18: 200 |
| Bäumers M, Klose S, Brüser C, et al. (2019) The auxiliary ESCRT complexes provide robustness to cold in poikilothermic organisms. Biology Open |
| Berndt N, Seib E, Kim S, et al. (2017) Ubiquitylation-independent activation of Notch signalling by Delta. Elife. 6 |
| Drusenheimer N, Migdal B, Jäckel S, et al. (2015) The Mammalian Orthologs of Drosophila Lgd, CC2D1A and CC2D1B, Function in the Endocytic Pathway, but Their Individual Loss of Function Does Not Affect Notch Signalling. Plos Genetics. 11: e1005749 |
| Gomez-Lamarca MJ, Snowdon LA, Seib E, et al. (2015) Rme-8 depletion perturbs Notch recycling and predisposes to pathogenic signaling. The Journal of Cell Biology. 210: 303-18 |
| Morawa KS, Schneider M, Klein T. (2015) Lgd regulates the activity of the BMP/Dpp signalling pathway during Drosophila oogenesis. Development (Cambridge, England). 142: 1325-35 |
| Yousefian J, Troost T, Grawe F, et al. (2013) Dmon1 controls recruitment of Rab7 to maturing endosomes in Drosophila. Journal of Cell Science. 126: 1583-94 |
| Schneider M, Troost T, Grawe F, et al. (2013) Activation of Notch in lgd mutant cells requires the fusion of late endosomes with the lysosome. Journal of Cell Science. 126: 645-56 |