Ryan R. Klimczak, Ph.D.
Affiliations: | 2010 | Molecular & Cell Biology | University of California, Berkeley, Berkeley, CA, United States |
Area:
Neuroscience , retinaGoogle:
"Ryan Klimczak"Mean distance: 16.6 (cluster 6) | S | N | B | C | P |
Parents
Sign in to add mentor| John G. Flannery | grad student | 2010 | UC Berkeley | |
| (Molecular evolution of adeno-associated virus for improved retinal gene therapies.) | ||||
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Publications
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| Pellissier LP, Hoek RM, Vos RM, et al. (2014) Specific tools for targeting and expression in Müller glial cells. Molecular Therapy. Methods & Clinical Development. 1: 14009 |
| Dalkara D, Byrne LC, Klimczak RR, et al. (2013) In vivo-directed evolution of a new adeno-associated virus for therapeutic outer retinal gene delivery from the vitreous. Science Translational Medicine. 5: 189ra76 |
| Dalkara D, Kolstad KD, Guerin KI, et al. (2011) AAV mediated GDNF secretion from retinal glia slows down retinal degeneration in a rat model of retinitis pigmentosa. Molecular Therapy : the Journal of the American Society of Gene Therapy. 19: 1602-8 |
| Lim KI, Klimczak R, Yu JH, et al. (2010) Specific insertions of zinc finger domains into Gag-Pol yield engineered retroviral vectors with selective integration properties. Proceedings of the National Academy of Sciences of the United States of America. 107: 12475-80 |
| Klimczak RR, Koerber JT, Dalkara D, et al. (2009) A novel adeno-associated viral variant for efficient and selective intravitreal transduction of rat Müller cells. Plos One. 4: e7467 |
| Dalkara D, Kolstad KD, Caporale N, et al. (2009) Inner limiting membrane barriers to AAV-mediated retinal transduction from the vitreous. Molecular Therapy : the Journal of the American Society of Gene Therapy. 17: 2096-102 |
| Koerber JT, Klimczak R, Jang JH, et al. (2009) Molecular evolution of adeno-associated virus for enhanced glial gene delivery. Molecular Therapy : the Journal of the American Society of Gene Therapy. 17: 2088-95 |