Jeffrey J. Lochhead, Ph.D.

Affiliations: 
2011 Neuroscience University of Arizona, Tucson, AZ 
Area:
Pain, opioids, pharmacology
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Thomas P. Davis grad student University of Arizona
Todd W. Vanderah grad student 2011 University of Arizona
 (Oxidative stress alters blood-brain barrier integrity.)
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Publications

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Williams EI, Betterton RD, Stanton JA, et al. (2023) Oatp (Organic Anion Transporting Polypeptide)-Mediated Transport: A Mechanism for Atorvastatin Neuroprotection in Stroke. Stroke. 54: 2875-2885
Lochhead JJ, Williams EI, Reddell ES, et al. (2023) High Resolution Multiplex Confocal Imaging of the Neurovascular Unit in Health and Experimental Ischemic Stroke. Cells. 12
Yang J, Betterton RD, Williams EI, et al. (2022) High-Dose Acetaminophen Alters the Integrity of the Blood-Brain Barrier and Leads to Increased CNS Uptake of Codeine in Rats. Pharmaceutics. 14
Kwak EA, Pan CC, Ramonett A, et al. (2022) β-spectrin as a stalk cell-intrinsic regulator of VEGF signaling. Nature Communications. 13: 1326
Lochhead JJ, Yang J, Ronaldson PT, et al. (2020) Structure, Function, and Regulation of the Blood-Brain Barrier Tight Junction in Central Nervous System Disorders. Frontiers in Physiology. 11: 914
Lochhead JJ, Davis TP. (2019) Perivascular and Perineural Pathways Involved in Brain Delivery and Distribution of Drugs after Intranasal Administration. Pharmaceutics. 11
Lochhead JJ, Kellohen KL, Ronaldson PT, et al. (2019) Distribution of insulin in trigeminal nerve and brain after intranasal administration. Scientific Reports. 9: 2621
Kumar NN, Lochhead JJ, Pizzo ME, et al. (2018) Delivery of immunoglobulin G antibodies to the rat nervous system following intranasal administration: Distribution, dose-response, and mechanisms of delivery. Journal of Controlled Release : Official Journal of the Controlled Release Society
Lochhead JJ, Ronaldson PT, Davis TP. (2017) Hypoxic Stress and Inflammatory Pain Disrupt Blood-Brain Barrier Tight Junctions: Implications for Drug Delivery to the Central Nervous System. The Aaps Journal
Kumar NN, Gautam M, Lochhead JJ, et al. (2016) Relative vascular permeability and vascularity across different regions of the rat nasal mucosa: implications for nasal physiology and drug delivery. Scientific Reports. 6: 31732
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