Kasey R. Hutt, Ph.D.
Affiliations: | 2009 | Bioinformatics | University of California, San Diego, La Jolla, CA |
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"Kasey Hutt"Mean distance: 17.02 (cluster 32)
Parents
Sign in to add mentor| Michael G. Rosenfeld | grad student | 2009 | UCSD | |
| (High-throughput genomic assays: Applications and analysis of DSL technology and next -generation sequencing.) | ||||
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Publications
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| Krach F, Batra R, C Wheeler E, et al. (2018) Transcriptome-pathology correlation identifies interplay between TDP-43 and the expression of its kinase CK1E in sporadic ALS. Acta Neuropathologica |
| Kapeli K, Pratt GA, Vu AQ, et al. (2016) Distinct and shared functions of ALS-associated proteins TDP-43, FUS and TAF15 revealed by multisystem analyses. Nature Communications. 7: 12143 |
| Concepcion D, Ross KD, Hutt KR, et al. (2015) Nxf1 natural variant E610G is a semi-dominant suppressor of IAP-induced RNA processing defects. Plos Genetics. 11: e1005123 |
| Benner C, Konovalov S, Mackintosh C, et al. (2013) Decoding a signature-based model of transcription cofactor recruitment dictated by cardinal cis-regulatory elements in proximal promoter regions. Plos Genetics. 9: e1003906 |
| Lagier-Tourenne C, Baughn M, Rigo F, et al. (2013) Targeted degradation of sense and antisense C9orf72 RNA foci as therapy for ALS and frontotemporal degeneration. Proceedings of the National Academy of Sciences of the United States of America. 110: E4530-9 |
| Lagier-Tourenne C, Polymenidou M, Hutt KR, et al. (2012) Divergent roles of ALS-linked proteins FUS/TLS and TDP-43 intersect in processing long pre-mRNAs. Nature Neuroscience. 15: 1488-97 |
| Wilbert ML, Huelga SC, Kapeli K, et al. (2012) LIN28 binds messenger RNAs at GGAGA motifs and regulates splicing factor abundance. Molecular Cell. 48: 195-206 |
| Polymenidou M, Lagier-Tourenne C, Hutt KR, et al. (2012) Misregulated RNA processing in amyotrophic lateral sclerosis. Brain Research. 1462: 3-15 |
| Polymenidou M, Lagier-Tourenne C, Hutt KR, et al. (2011) Long pre-mRNA depletion and RNA missplicing contribute to neuronal vulnerability from loss of TDP-43. Nature Neuroscience. 14: 459-68 |
| Zisoulis DG, Lovci MT, Wilbert ML, et al. (2010) Comprehensive discovery of endogenous Argonaute binding sites in Caenorhabditis elegans. Nature Structural & Molecular Biology. 17: 173-9 |