Jason M. Uslaner, Ph.D.

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2003 University of Michigan, Ann Arbor, Ann Arbor, MI 
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Terry E. Robinson grad student 2003 University of Michigan
 (The influence of context, dose, and drug history on the neurobiological effects of amphetamine and cocaine.)
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Publications

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Vardigan JD, Lange HS, Tye SJ, et al. (2016) Behavioral and qEEG effects of the PDE10A inhibitor THPP-1 in a novel rhesus model of antipsychotic activity. Psychopharmacology
Stachel SJ, Zerbinatti C, Rudd MT, et al. (2016) Identification and In Vivo Evaluation of Liver X Receptor β (LXRβ) Selective Agonists for the Potential Treatment of Alzheimer's Disease. Journal of Medicinal Chemistry
Pero JE, Rossi MA, Kelly MJ, et al. (2016) Optimization of Novel Aza-benzimidazolone mGluR2 PAMs with Respect to LLE and PK Properties and Mitigation of CYP TDI. Acs Medicinal Chemistry Letters. 7: 312-7
Layton ME, Reif AJ, Hartingh TJ, et al. (2016) Discovery of 5-aryl-1,3-dihydro-2H-imidazo[4,5-b]pyridin-2-ones as positive allosteric modulators of metabotropic glutamate subtype-2 (mGlu2) receptors with efficacy in a preclinical model of psychosis. Bioorganic & Medicinal Chemistry Letters
Tannenbaum PL, Tye SJ, Stevens J, et al. (2016) Inhibition of orexin signaling promotes sleep yet preserves salient arousability in monkeys Sleep. 39: 603-612
Raheem IT, Schreier JD, Fuerst J, et al. (2015) Discovery of pyrazolopyrimidine phosphodiesterase 10A inhibitors for the treatment of schizophrenia. Bioorganic & Medicinal Chemistry Letters
Zhao F, Wang X, Zariwala HA, et al. (2015) fMRI study of olfaction in the olfactory bulb and high olfactory structures of rats: Insight into their roles in habituation. Neuroimage
Lange HS, Cannon CE, Drott JT, et al. (2015) The M1 Muscarinic Positive Allosteric Modulator PQCA Improves Performance on Translatable Tests of Memory and Attention in Rhesus Monkeys. The Journal of Pharmacology and Experimental Therapeutics. 355: 442-50
Shipe WD, Sharik SS, Barrow JC, et al. (2015) Discovery and Optimization of a Series of Pyrimidine-Based Phosphodiesterase 10A (PDE10A) Inhibitors through Fragment Screening, Structure-Based Design, and Parallel Synthesis. Journal of Medicinal Chemistry
Gentzel RC, Toolan D, Roberts R, et al. (2015) The PDE10A inhibitor MP-10 and haloperidol produce distinct gene expression profiles in the striatum and influence cataleptic behavior in rodents. Neuropharmacology
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