Jason M. Uslaner, Ph.D.
Affiliations: | 2003 | University of Michigan, Ann Arbor, Ann Arbor, MI |
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"Jason Uslaner"Mean distance: 14.84 (cluster 19) | S | N | B | C | P |
Parents
Sign in to add mentor| Terry E. Robinson | grad student | 2003 | University of Michigan | |
| (The influence of context, dose, and drug history on the neurobiological effects of amphetamine and cocaine.) | ||||
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Publications
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| Shu Y, Diamond TL, Hershey JC, et al. (2020) Discovery of 4-arylquinoline-2-carboxamides, highly potent and selective class of mGluR2 negative allosteric modulators: From HTS to activity in animal models. Bioorganic & Medicinal Chemistry Letters. 127066 |
| Wang X, Daley C, Gakhar V, et al. (2020) Pharmacological characterization of the novel and selective α7 nicotinic acetylcholine receptor positive allosteric modulator BNC375. The Journal of Pharmacology and Experimental Therapeutics |
| Schubert JW, Harrison ST, Mulhearn J, et al. (2019) Discovery, Optimization, and Biological Characterization of 2,3,6-Trisubstituted Pyridine-Containing M Positive Allosteric Modulators. Chemmedchem |
| Zhao F, Holahan MA, Wang X, et al. (2018) fMRI study of the role of glutamate NMDA receptor in the olfactory processing in monkeys. Plos One. 13: e0198395 |
| Uslaner JM, Kuduk SD, Wittmann M, et al. (2018) Preclinical to Human Translational Pharmacology of the Novel MPositive Allosteric Modulator MK-7622. The Journal of Pharmacology and Experimental Therapeutics |
| Yao LL, Ramirez A, Roecker AJ, et al. (2017) The dual orexin receptor antagonist, DORA-22, lowers histamine levels in the lateral hypothalamus and prefrontal cortex without lowering hippocampal acetylcholine. Journal of Neurochemistry |
| Vardigan JD, Lange HS, Tye SJ, et al. (2016) Behavioral and qEEG effects of the PDE10A inhibitor THPP-1 in a novel rhesus model of antipsychotic activity. Psychopharmacology |
| Pero JE, Rossi MA, Kelly MJ, et al. (2016) Optimization of Novel Aza-benzimidazolone mGluR2 PAMs with Respect to LLE and PK Properties and Mitigation of CYP TDI. Acs Medicinal Chemistry Letters. 7: 312-7 |
| Layton ME, Reif AJ, Hartingh TJ, et al. (2016) Discovery of 5-aryl-1,3-dihydro-2H-imidazo[4,5-b]pyridin-2-ones as positive allosteric modulators of metabotropic glutamate subtype-2 (mGlu2) receptors with efficacy in a preclinical model of psychosis. Bioorganic & Medicinal Chemistry Letters |
| Raheem IT, Schreier JD, Fuerst J, et al. (2015) Discovery of pyrazolopyrimidine phosphodiesterase 10A inhibitors for the treatment of schizophrenia. Bioorganic & Medicinal Chemistry Letters |