William R. Silverman, Ph.D.

Affiliations: 
2002 University of California, Los Angeles, Los Angeles, CA 
Area:
K Channels
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"William Silverman"
Mean distance: 18.04 (cluster 11)
 

Parents

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Diane M. Papazian grad student 2002 UCLA
 (Structural interactions in the voltage sensor of potassium channels derived from metal ion coordination in ether-a-go-go.)
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Publications

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Silverman WR, de Rivero Vaccari JP, Locovei S, et al. (2009) The pannexin 1 channel activates the inflammasome in neurons and astrocytes. The Journal of Biological Chemistry. 284: 18143-51
Altieri SL, Clayton GM, Silverman WR, et al. (2008) Structural and energetic analysis of activation by a cyclic nucleotide binding domain. Journal of Molecular Biology. 381: 655-69
Silverman W, Locovei S, Dahl G. (2008) Probenecid, a gout remedy, inhibits pannexin 1 channels. American Journal of Physiology. Cell Physiology. 295: C761-7
Silverman WR, Heginbotham L. (2007) The MlotiK1 channel transports ions along the canonical conduction pore. Febs Letters. 581: 5024-8
Díez-Sampedro A, Silverman WR, Bautista JF, et al. (2006) Mechanism of increased open probability by a mutation of the BK channel. Journal of Neurophysiology. 96: 1507-16
Clayton GM, Silverman WR, Heginbotham L, et al. (2004) Structural basis of ligand activation in a cyclic nucleotide regulated potassium channel. Cell. 119: 615-27
Silverman WR, Bannister JP, Papazian DM. (2004) Binding site in eag voltage sensor accommodates a variety of ions and is accessible in closed channel. Biophysical Journal. 87: 3110-21
Lainé M, Lin MC, Bannister JP, et al. (2003) Atomic proximity between S4 segment and pore domain in Shaker potassium channels. Neuron. 39: 467-81
Silverman WR, Roux B, Papazian DM. (2003) Structural basis of two-stage voltage-dependent activation in K+ channels. Proceedings of the National Academy of Sciences of the United States of America. 100: 2935-40
Papazian DM, Silverman WR, Lin MC, et al. (2002) Structural organization of the voltage sensor in voltage-dependent potassium channels. Novartis Foundation Symposium. 245: 178-90; discussion 1
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