Tinatin I. Brelidze, Ph.D.
Affiliations: | 2003 | Pharmacology | University of Miami, Coral Gables, FL |
Area:
molecular mechanisms of ion channel regulationWebsite:
https://pharmacology.georgetown.edu/people/faculty/brelidze-2/Google:
"Tina Brelidze"Mean distance: 15.12 (cluster 46) | S | N | B | C | P |
Parents
Sign in to add mentor| Karl L. Magleby | grad student | 2003 | University of Miami | |
| (Limits and contributing mechanisms for big single -channel currents in BK channels.) | ||||
| William N. Zagotta | post-doc | University of Washington | ||
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Publications
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| Tiwari PB, Kamgar-Dayhoff P, Tiwari P, et al. (2024) Use of Surface Plasmon Resonance Technique for Studies of Inter-domain Interactions in Ion Channels. Methods in Molecular Biology (Clifton, N.J.). 2796: 105-118 |
| Ghorbani M, Wang ZJ, Chen X, et al. (2024) Chlorpromazine inhibits EAG1 channels by altering the coupling between the PAS, CNBH and pore domains. Biorxiv : the Preprint Server For Biology |
| Wang ZJ, Ghorbani M, Chen X, et al. (2023) Molecular Mechanism of EAG1 Channel Inhibition by Imipramine Binding to the PAS domain. The Journal of Biological Chemistry. 105391 |
| Brelidze TI. (2023) Heteromeric wild-type/mutant potassium channel subunit composition as a major determinant of channelopathy phenotype in heterozygous patients. The Journal of General Physiology. 155 |
| Soohoo SM, Tiwari PB, Suzuki YJ, et al. (2022) Investigation of PAS and CNBH domain interactions in hERG channels and effects of long-QT syndrome-causing mutations with surface plasmon resonance. The Journal of Biological Chemistry. 298: 101433 |
| Wang ZJ, Blanco I, Hayoz S, et al. (2020) The HCN domain is required for HCN channel cell-surface expression and couples voltage- and cAMP-dependent gating mechanisms. The Journal of Biological Chemistry |
| Wang ZJ, Soohoo SM, Tiwari PB, et al. (2020) Chlorpromazine binding to the PAS domains uncovers the effect of ligand modulation on EAG channel activity. The Journal of Biological Chemistry |
| Shults NV, Rybka V, Suzuki Y, et al. (2020) Expression of Kv11.1 Channels in Lungs and Role in Pulmonary Hypertension The Faseb Journal. 34: 1-1 |
| Wang Z, Kamgar-Dayhoff P, Tiwari PB, et al. (2020) EAG Channel PAS Domain Binder Inhibits Currents from EAG Channels and Decreases Tumor Growth in Zebrafish Xenograft Model Biophysical Journal. 118: 268a |
| Wang Z, Blanco I, Brelidze TI. (2020) HCN Domain is Necessary for Surface Expression of HCN Channels Biophysical Journal. 118: 261a |