John Hines, Ph.D.

2000 University of Pennsylvania, Philadelphia, PA, United States 
"John Hines"
Mean distance: 18.21 (cluster 19)


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Steven J. Fluharty grad student 2000 Penn
 (Structural determinants for functional properties of angiotensin II receptors.)
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Lu J, Qian Y, Altieri M, et al. (2015) Hijacking the E3 Ubiquitin Ligase Cereblon to Efficiently Target BRD4. Chemistry & Biology. 22: 755-63
Hines J, Gough JD, Corson TW, et al. (2013) Posttranslational protein knockdown coupled to receptor tyrosine kinase activation with phosphoPROTACs. Proceedings of the National Academy of Sciences of the United States of America. 110: 8942-7
Holman EC, Campbell LJ, Hines J, et al. (2012) Microarray analysis of microRNA expression during axolotl limb regeneration. Plos One. 7: e41804
Tae HS, Hines J, Schneekloth AR, et al. (2011) Unexpected stereochemical tolerance for the biological activity of tyroscherin. Bioorganic & Medicinal Chemistry. 19: 1708-13
Tae HS, Hines J, Schneekloth AR, et al. (2010) Total synthesis and biological evaluation of tyroscherin. Organic Letters. 12: 4308-11
Hines J, Ju R, Dutschman GE, et al. (2010) Reversal of TNP-470-induced endothelial cell growth arrest by guanine and guanine nucleosides. The Journal of Pharmacology and Experimental Therapeutics. 334: 729-38
Custar DW, Zabawa TP, Hines J, et al. (2009) Total synthesis and structure-activity investigation of the marine natural product neopeltolide. Journal of the American Chemical Society. 131: 12406-14
Hines J, Groll M, Fahnestock M, et al. (2008) Proteasome inhibition by fellutamide B induces nerve growth factor synthesis. Chemistry & Biology. 15: 501-12
Zhang Y, Yeh JR, Mara A, et al. (2006) A chemical and genetic approach to the mode of action of fumagillin. Chemistry & Biology. 13: 1001-9
Hines J, Roy M, Cheng H, et al. (2006) Myriaporone 3/4 structure--activity relationship studies define a pharmacophore targeting eukaryotic protein synthesis. Molecular Biosystems. 2: 371-9
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