Jeffrey D. Calhoun, Ph.D.

Affiliations: 
2013 Cellular and Molecular Biology University of Michigan, Ann Arbor, Ann Arbor, MI 
Area:
Sodium Channels
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"Jeffrey Calhoun"
Mean distance: 17.55 (cluster 11)
 
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Lori Isom grad student 2013 University of Michigan
 (Role of voltage-gated sodium channel beta subunit signaling in neuronal development and cancer.)
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Publications

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Bouza AA, Philippe JM, Edokobi N, et al. (2020) Sodium channel β1 subunits are post-translationally modified by tyrosine phosphorylation, S-palmitoylation, and regulated intramembrane proteolysis. The Journal of Biological Chemistry
Kang SK, Vanoye CG, Misra SN, et al. (2019) Spectrum of K 2.1 Dysfunction in KCNB1-Associated Neurodevelopmental Disorders. Annals of Neurology
Lamar T, Vanoye CG, Calhoun J, et al. (2017) SCN3A deficiency associated with increased seizure susceptibility. Neurobiology of Disease
Calhoun JD, Hawkins NA, Zachwieja NJ, et al. (2016) Cacna1g is a genetic modifier of epilepsy caused by mutation of voltage-gated sodium channel Scn2a. Epilepsia
Calhoun JD, Isom LL. (2014) The role of non-pore-forming β subunits in physiology and pathophysiology of voltage-gated sodium channels. Handbook of Experimental Pharmacology. 221: 51-89
Chen C, Calhoun JD, Zhang Y, et al. (2012) Identification of the cysteine residue responsible for disulfide linkage of Na+ channel α and β2 subunits. The Journal of Biological Chemistry. 287: 39061-9
Yang M, Kozminski DJ, Wold LA, et al. (2012) Therapeutic potential for phenytoin: targeting Na(v)1.5 sodium channels to reduce migration and invasion in metastatic breast cancer. Breast Cancer Research and Treatment. 134: 603-15
Nguyen HM, Calhoun JD, Isom LL, et al. (2012) Modulation of Kv1 Voltage-Gated Potassium Channels by Sodium Channel Beta Subunits Biophysical Journal. 102: 687a
Patino GA, Brackenbury WJ, Bao Y, et al. (2011) Voltage-gated Na+ channel β1B: a secreted cell adhesion molecule involved in human epilepsy. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 14577-91
Brackenbury WJ, Calhoun JD, Chen C, et al. (2010) Functional reciprocity between Na+ channel Nav1.6 and beta1 subunits in the coordinated regulation of excitability and neurite outgrowth. Proceedings of the National Academy of Sciences of the United States of America. 107: 2283-8
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