Joshua P. Thaler, Ph.D.

Affiliations: 
2001 University of California, San Diego, La Jolla, CA 
Area:
Development
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"Joshua Thaler"
Mean distance: 15.8 (cluster 11)
 
SNBCP

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Samuel L. Pfaff grad student 2001 UCSD
 (How to make a motor neuron: 2 parts LIM, 1 part HB9 with a spritz of sonic.)
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Publications

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Meek TH, Nelson JT, Matsen ME, et al. (2016) Functional identification of a neurocircuit regulating blood glucose. Proceedings of the National Academy of Sciences of the United States of America
Dorfman MD, Thaler JP. (2015) Hypothalamic inflammation and gliosis in obesity. Current Opinion in Endocrinology, Diabetes, and Obesity. 22: 325-30
Berkseth KE, Guyenet SJ, Melhorn SJ, et al. (2014) Hypothalamic gliosis associated with high-fat diet feeding is reversible in mice: a combined immunohistochemical and magnetic resonance imaging study. Endocrinology. 155: 2858-67
Gao Y, Ottaway N, Schriever SC, et al. (2014) Hormones and diet, but not body weight, control hypothalamic microglial activity. Glia. 62: 17-25
Karatsoreos IN, Thaler JP, Borgland SL, et al. (2013) Food for thought: hormonal, experiential, and neural influences on feeding and obesity. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 17610-6
Thaler JP, Guyenet SJ, Dorfman MD, et al. (2013) Hypothalamic inflammation: marker or mechanism of obesity pathogenesis? Diabetes. 62: 2629-34
Lee D, Thaler JP, Berkseth KE, et al. (2013) Longer T(2) relaxation time is a marker of hypothalamic gliosis in mice with diet-induced obesity. American Journal of Physiology. Endocrinology and Metabolism. 304: E1245-50
Guyenet SJ, Nguyen HT, Hwang BH, et al. (2013) High-fat diet feeding causes rapid, non-apoptotic cleavage of caspase-3 in astrocytes. Brain Research. 1512: 97-105
Matsen ME, Thaler JP, Wisse BE, et al. (2013) In uncontrolled diabetes, thyroid hormone and sympathetic activators induce thermogenesis without increasing glucose uptake in brown adipose tissue. American Journal of Physiology. Endocrinology and Metabolism. 304: E734-46
Meek TH, Wisse BE, Thaler JP, et al. (2013) BDNF action in the brain attenuates diabetic hyperglycemia via insulin-independent inhibition of hepatic glucose production. Diabetes. 62: 1512-8
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