Jonathan M. Brotchie

Affiliations: 
Toronto Western Research Institute, Toronto, Ontario, Canada 
Area:
neurodegenerative disorders
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"Jonathan Brotchie"
Mean distance: 16.93 (cluster 6)
 
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Publications

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Howson PA, Johnston TH, Ravenscroft P, et al. (2019) Beneficial effects of trehalose on striatal dopaminergic deficits in rodent and primate models of synucleinopathy in Parkinson's disease. The Journal of Pharmacology and Experimental Therapeutics
Johnston TH, Geva M, Steiner L, et al. (2018) Pridopidine, a clinic-ready compound, reduces 3,4-dihydroxyphenylalanine-induced dyskinesia in Parkinsonian macaques. Movement Disorders : Official Journal of the Movement Disorder Society
Fox SH, Brotchie JM. (2018) Viewpoint: Developing drugs for levodopa-induced dyskinesia in PD: Lessons learnt, what does the future hold? The European Journal of Neuroscience
Johnston TH, Lacoste AMB, Visanji NP, et al. (2018) Repurposing drugs to treat l-DOPA-induced dyskinesia in Parkinson's disease. Neuropharmacology
Gleave JA, Arathoon LR, Trinh D, et al. (2018) Corrigendum to "Sirtuin 3 rescues neurons through the stabilisation of mitochondrial biogenetics in the virally-expressing mutant α-synuclein rat model of parkinsonism" [Neurobiol. Dis. 106 (2018) 133-146]. Neurobiology of Disease
Johnston TH, Versi E, Howson PA, et al. (2017) DPI-289, a novel mixed delta opioid agonist / mu opioid antagonist (DAMA), has L-DOPA-sparing potential in Parkinson's disease. Neuropharmacology
Arathoon LR, Gleave JA, Trinh D, et al. (2017) Sirtuin 3 rescues neurons through the stabilisation of mitochondrial biogenetics in the virally-expressing mutant α-synuclein rat model of parkinsonism. Neurobiology of Disease
Huot P, Fox SH, Brotchie JM. (2016) Dopamine Reuptake Inhibitors in Parkinson's Disease: A Review of Nonhuman Primate Studies and Clinical Trials. The Journal of Pharmacology and Experimental Therapeutics. 357: 562-9
Ma Y, Johnston TH, Peng S, et al. (2015) Reproducibility of a Parkinsonism-related metabolic brain network in non-human primates: A descriptive pilot study with FDG PET. Movement Disorders : Official Journal of the Movement Disorder Society. 30: 1283-8
Kim HK, Mendonça KM, Howson PA, et al. (2015) The link between mitochondrial complex I and brain-derived neurotrophic factor in SH-SY5Y cells - The potential of JNX1001 as a therapeutic agent. European Journal of Pharmacology. 764: 379-84
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