Shirish Shenolikar

Affiliations: 
Duke University, Durham, NC 
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"Shirish Shenolikar"
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Children

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Carey J. Oliver grad student 2001 Duke
Ryan T. Terry-Lorenzo grad student 2002 Duke
James W. Voltz grad student 2004 Duke
Douglas C. Weiser grad student 2004 Duke
Matthew H. Brush grad student 2005 Duke
David W. Roadcap grad student 2005 Duke
Jennifer A. Gibbons grad student 2006 Duke
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Publications

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Sundaram JR, Wu Y, Lee IC, et al. (2019) PromISR-6, a Guanabenz Analogue, Improves Cellular Survival in an Experimental Model of Huntington's Disease. Acs Chemical Neuroscience
Goh CW, Lee IC, Sundaram JR, et al. (2017) Chronic oxidative stress promotes GADD34-mediated phosphorylation of the TAR DNA-binding protein TDP-43, a modification linked to neurodegeneration. The Journal of Biological Chemistry
Lee IC, Ho XY, George SE, et al. (2017) Oxidative stress promotes SIRT1 recruitment to the GADD34/PP1α complex to activate its deacetylase function. Cell Death and Differentiation
Sundaram JR, Lee IC, Shenolikar S. (2017) Translating protein phosphatase research into treatments for neurodegenerative diseases. Biochemical Society Transactions. 45: 101-112
Reid DW, Tay AS, Sundaram JR, et al. (2016) Complementary roles of GADD34- and CReP-containing eIF2α Phosphatases during the Unfolded Protein Response. Molecular and Cellular Biology
Reid DW, Shenolikar S, Nicchitta CV. (2015) Simple and inexpensive ribosome profiling analysis of mRNA translation. Methods (San Diego, Calif.)
Choy MS, Yusoff P, Lee IC, et al. (2015) Structural and Functional Analysis of the GADD34:PP1 eIF2α Phosphatase. Cell Reports. 11: 1885-91
Reid DW, Chen Q, Tay AS, et al. (2014) The unfolded protein response triggers selective mRNA release from the endoplasmic reticulum. Cell. 158: 1362-74
Shenolikar S. (2014) Dangerous liaisons: flirtations between oncogenic BRAF and GRP78 in drug-resistant melanomas. The Journal of Clinical Investigation. 124: 973-6
Zhou W, Jeyaraman K, Yusoff P, et al. (2013) Phosphorylation at tyrosine 262 promotes GADD34 protein turnover. The Journal of Biological Chemistry. 288: 33146-55
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