Daniel W. Sirkis
Affiliations: | University of California, San Francisco, San Francisco, CA |
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"Daniel Sirkis"Mean distance: 16.6 (cluster 32) | S | N | B | C | P |
Parents
Sign in to add mentor| Robert H. Edwards | grad student | 2007-2012 | UCSF | |
| (Role of Adaptor Protein AP-3 in Biogenesis of the Regulated Secretory Pathway.) | ||||
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Publications
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| Bonham LW, Sirkis DW, Yokoyama JS. (2019) The Transcriptional Landscape of Microglial Genes in Aging and Neurodegenerative Disease. Frontiers in Immunology. 10: 1170 |
| Geier EG, Bourdenx M, Storm NJ, et al. (2018) Rare variants in the neuronal ceroid lipofuscinosis gene MFSD8 are candidate risk factors for frontotemporal dementia. Acta Neuropathologica |
| Sirkis DW, Aparicio RE, Schekman R. (2017) Neurodegeneration-associated mutant TREM2 proteins abortively cycle between the ER and ER-Golgi intermediate compartment. Molecular Biology of the Cell |
| Bonham LW, Sirkis DW, Fan J, et al. (2017) Identification of a rare coding variant in TREM2 in a Chinese individual with Alzheimer's disease. Neurocase. 23: 65-69 |
| Sirkis DW, Bonham LW, Aparicio RE, et al. (2016) Rare TREM2 variants associated with Alzheimer's disease display reduced cell surface expression. Acta Neuropathologica Communications. 4: 98 |
| Guo Y, Sirkis DW, Schekman R. (2014) Protein sorting at the trans-Golgi network. Annual Review of Cell and Developmental Biology. 30: 169-206 |
| Asensio CS, Sirkis DW, Maas JW, et al. (2013) Self-assembly of VPS41 promotes sorting required for biogenesis of the regulated secretory pathway. Developmental Cell. 27: 425-37 |
| Sirkis DW, Edwards RH, Asensio CS. (2013) Widespread dysregulation of peptide hormone release in mice lacking adaptor protein AP-3. Plos Genetics. 9: e1003812 |
| Asensio CS, Sirkis DW, Edwards RH. (2010) RNAi screen identifies a role for adaptor protein AP-3 in sorting to the regulated secretory pathway. The Journal of Cell Biology. 191: 1173-87 |