Laura B. Pritzker, Ph.D.

Affiliations: 
2000 University of Toronto, Toronto, ON, Canada 
Area:
Myelin Basic Protein in Multiple Sclerosis
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"Laura Pritzker"
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Mario A. Moscarello grad student 2000 University of Toronto
 (The deimination of myelin basic protein as a post-translational modification contributing to the pathogenesis of demyelinating disease.)
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Publications

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Moscarello MA, Pritzker L, Mastronardi FG, et al. (2002) Peptidylarginine deiminase: a candidate factor in demyelinating disease. Journal of Neurochemistry. 81: 335-43
Pritzker LB, Joshi S, Harauz G, et al. (2000) Deimination of myelin basic protein. 2. Effect of methylation of MBP on its deimination by peptidylarginine deiminase. Biochemistry. 39: 5382-8
Pritzker LB, Joshi S, Gowan JJ, et al. (2000) Deimination of myelin basic protein. 1. Effect of deimination of arginyl residues of myelin basic protein on its structure and susceptibility to digestion by cathepsin D. Biochemistry. 39: 5374-81
Pritzker LB, Nguyen TA, Moscarello MA. (1999) The developmental expression and activity of peptidylarginine deiminase in the mouse. Neuroscience Letters. 266: 161-4
Pritzker LB, Moscarello MA. (1998) A novel microtubule independent effect of paclitaxel: the inhibition of peptidylarginine deiminase from bovine brain. Biochimica Et Biophysica Acta. 1388: 154-60
Costentino M, Pritzker L, Boulias C, et al. (1994) Acylation of myelin basic protein peptide 1-21 with alkyl carboxylates 2-10 carbons long affects secondary structure and posttranslational modification. Biochemistry. 33: 4155-62
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