William G. Barnes, Ph.D.

Affiliations: 
2003 Albany Medical College of Union University 
Area:
Pain research
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Parents

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Lindsay B. Hough grad student 2003 Albany Medical College of Union University
 (The termination of histamine transmission in the brain: Membrane localization and isoform studies of histamine N -methyltransferase.)
Robert J. Lefkowitz post-doc Duke
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Publications

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Violin JD, Dewire SM, Barnes WG, et al. (2006) G protein-coupled receptor kinase and beta-arrestin-mediated desensitization of the angiotensin II type 1A receptor elucidated by diacylglycerol dynamics. The Journal of Biological Chemistry. 281: 36411-9
Taraschenko OD, Barnes WG, Herrick-Davis K, et al. (2005) Actions of tacrine and galanthamine on histamine-N-methyltransferase. Methods and Findings in Experimental and Clinical Pharmacology. 27: 161-5
Hunton DL, Barnes WG, Kim J, et al. (2005) Beta-arrestin 2-dependent angiotensin II type 1A receptor-mediated pathway of chemotaxis. Molecular Pharmacology. 67: 1229-36
Barnes WG, Reiter E, Violin JD, et al. (2005) beta-Arrestin 1 and Galphaq/11 coordinately activate RhoA and stress fiber formation following receptor stimulation. The Journal of Biological Chemistry. 280: 8041-50
Wei H, Ahn S, Barnes WG, et al. (2004) Stable interaction between beta-arrestin 2 and angiotensin type 1A receptor is required for beta-arrestin 2-mediated activation of extracellular signal-regulated kinases 1 and 2. The Journal of Biological Chemistry. 279: 48255-61
Barnes WG, Grinde E, Crawford DR, et al. (2004) Characterization of a new mRNA species from the human histamine N-methyltransferase gene. Genomics. 83: 168-71
Barnes WG, Hough LB. (2002) Membrane-bound histamine N-methyltransferase in mouse brain: possible role in the synaptic inactivation of neuronal histamine. Journal of Neurochemistry. 82: 1262-71
Barnes W, Boyd D, Hough L. (2001) Dynamics of histamine H(3) receptor antagonists on brain histamine metabolism: do all histamine H(3) receptor antagonists act at a single site? European Journal of Pharmacology. 431: 215-21
Hough LB, Nalwalk JW, Barnes WG, et al. (2000) A third life for burimamide. Discovery and characterization of a novel class of non-opioid analgesics derived from histamine antagonists. Annals of the New York Academy of Sciences. 909: 25-40
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