Kelly L. McCoy, Ph.D.
Affiliations: | 2010 | Biological and Biomedical Sciences | Emory University, Atlanta, GA |
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"Kelly McCoy"Mean distance: 17.73 (cluster 6) | S | N | B | C | P |
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Sign in to add mentor| John Raymond Hepler | grad student | 2010 | Emory | |
| (Signaling and regulation of protease-activated receptors 1 and 2 (PAR1 and PAR2).) | ||||
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Publications
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| Ghil S, McCoy KL, Hepler JR. (2014) Regulator of G protein signaling 2 (RGS2) and RGS4 form distinct G protein-dependent complexes with protease activated-receptor 1 (PAR1) in live cells. Plos One. 9: e95355 |
| McCoy KL, Gyoneva S, Vellano CP, et al. (2012) Protease-activated receptor 1 (PAR1) coupling to G(q/11) but not to G(i/o) or G(12/13) is mediated by discrete amino acids within the receptor second intracellular loop. Cellular Signalling. 24: 1351-60 |
| McCoy KL, Traynelis SF, Hepler JR. (2010) PAR1 and PAR2 couple to overlapping and distinct sets of G proteins and linked signaling pathways to differentially regulate cell physiology. Molecular Pharmacology. 77: 1005-15 |
| McCoy KL, Hepler JR. (2009) Regulators of G protein signaling proteins as central components of G protein-coupled receptor signaling complexes. Progress in Molecular Biology and Translational Science. 86: 49-74 |
| Mannaioni G, Orr AG, Hamill CE, et al. (2008) Plasmin potentiates synaptic N-methyl-D-aspartate receptor function in hippocampal neurons through activation of protease-activated receptor-1. The Journal of Biological Chemistry. 283: 20600-11 |
| Zhou H, Yu K, McCoy KL, et al. (2005) Molecular mechanism for divergent regulation of Cav1.2 Ca2+ channels by calmodulin and Ca2+-binding protein-1. The Journal of Biological Chemistry. 280: 29612-9 |