Lennart Mucke
Affiliations: | Gladstone Institute/UCSF, San Francisco, CA, United States | ||
University of California, San Francisco, San Francisco, CA |
Area:
Neurobiology of Diseases Affecting Cognitive FunctionsGoogle:
"Lennart Mucke"Mean distance: 12.44 (cluster 6) | S | N | B | C | P |
Parents
Sign in to add mentorOtto D. Creutzfeldt | post-doc | 1982-1984 | Max Planck Institute |
Michael B. Oldstone | post-doc | 1988-1990 | Scripps Institute |
Children
Sign in to add traineeHilary B. Gerstein | research assistant | 2004-2006 | Gladstone Institute of Neurological Disease |
Paul Larkin | grad student | 2012 | UCSF |
Jeannie Chin | post-doc | Gladstone Institute | |
Dena B. Dubal | post-doc | UCSF | |
Li Gan | post-doc | Gladstone Institute | |
Julie A. Harris | post-doc | Gladstone Institute | |
Jorge J. Palop | post-doc | Gladstone and UCSF | |
Keith A. Vossel | post-doc | Gladstone Institute of Neurological Disease | |
Tony Wyss-Coray | post-doc | 1993-1995 | Scripps Institute |
Irene H. Cheng | post-doc | 2002-2007 | Gladstone Institute |
Kimberly A. Scearce-Levie | post-doc | 2002-2007 | Gladstone Institute |
Scott A. Wellnitz | post-doc | 2012-2013 | Gladstone Institute (UCSF) |
Erik Roberson | research scientist | 2003-2006 | Gladstone Institute |
Collaborators
Sign in to add collaboratorCarmela R. Abraham | collaborator | 1990- | UCSF (Gladstone Institutes) |
BETA: Related publications
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Publications
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Das M, Mao W, Voskobiynyk Y, et al. (2023) Alzheimer risk-increasing TREM2 variant causes aberrant cortical synapse density and promotes network hyperexcitability in mouse models. Neurobiology of Disease. 106263 |
Shao E, Chang CW, Li Z, et al. (2022) TAU ablation in excitatory neurons and postnatal TAU knockdown reduce epilepsy, SUDEP, and autism behaviors in a Dravet syndrome model. Science Translational Medicine. 14: eabm5527 |
Das M, Mao W, Shao E, et al. (2021) Interdependence of neural network dysfunction and microglial alterations in Alzheimer's disease-related models. Iscience. 24: 103245 |
Chang CW, Evans MD, Yu X, et al. (2021) Tau reduction affects excitatory and inhibitory neurons differently, reduces excitation/inhibition ratios, and counteracts network hypersynchrony. Cell Reports. 37: 109855 |
Vossel K, Ranasinghe KG, Beagle AJ, et al. (2021) Effect of Levetiracetam on Cognition in Patients With Alzheimer Disease With and Without Epileptiform Activity: A Randomized Clinical Trial. Jama Neurology |
Gulbranson DR, Ho K, Yu GQ, et al. (2021) Phenotypic differences between the Alzheimer's disease-related hAPP-J20 model and heterozygous knockout mice. Eneuro |
Chang CW, Shao E, Mucke L. (2021) Tau: Enabler of diverse brain disorders and target of rapidly evolving therapeutic strategies. Science (New York, N.Y.). 371 |
Johnson ECB, Ho K, Yu GQ, et al. (2020) Behavioral and neural network abnormalities in human APP transgenic mice resemble those of App knock-in mice and are modulated by familial Alzheimer's disease mutations but not by inhibition of BACE1. Molecular Neurodegeneration. 15: 53 |
Davis EJ, Broestl L, Abdulai-Saiku S, et al. (2020) A second X chromosome contributes to resilience in a mouse model of Alzheimer's disease. Science Translational Medicine. 12 |
Tai C, Chang CW, Yu GQ, et al. (2020) Tau Reduction Prevents Key Features of Autism in Mouse Models. Neuron |