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Timothy A. Springer

Biological Chemistry & Molecular Pharmacology Harvard Medical School, Boston, MA, United States 
"Timothy A. Springer"

Mean distance: 16.7 (cluster 11)
Cross-listing: Chemistry Tree


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Jack L. Strominger grad student 1976 Harvard (Chemistry Tree)
 (Detergent soluble products of HLA)
César Milstein post-doc 1976-1977 MRC-LMB


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Jongseong Kim grad student Harvard Medical School
Xing CHEN post-doc 2007-2010 Harvard Medical School (Chemistry Tree)
Mehmet Sen post-doc 2007-2015 Harvard Medical School - Boston Children's Hospital (Chemistry Tree)


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Joseph Mathew Kalappurakkal collaborator (Cell Biology Tree)
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Jiang Y, Fu H, Springer TA, et al. (2019) Electrostatic Steering Enables Flow-Activated von Willebrand Factor to Bind Platelet Glycoprotein, Revealed by Single-Molecule Stretching and Imaging. Journal of Molecular Biology
Dong X, Leksa NC, Chhabra ES, et al. (2019) The von Willebrand factor D'D3 assembly and structural principles for factor VIII binding and concatemer biogenesis. Blood
Beilin C, Choudhuri K, Bouma G, et al. (2018) Dendritic cell-expressed common gamma-chain recruits IL-15 for trans-presentation at the murine immunological synapse. Wellcome Open Research. 3: 84
Feng J, Dong X, Pinello J, et al. (2018) Fusion surface structure, function, and dynamics of gamete fusogen HAP2. Elife. 7
Qin Y, Garrison BS, Ma W, et al. (2018) A Milieu Molecule for TGF-β Required for Microglia Function in the Nervous System. Cell
Sen M, Koksal AC, Yuki K, et al. (2018) Ligand and cation-induced structural alterations of the leukocyte integrin LFA-1. The Journal of Biological Chemistry
Dong X, Zhao B, Lin FY, et al. (2018) High integrin αVβ6 affinity reached by hybrid domain deletion slows ligand-binding on-rate. Proceedings of the National Academy of Sciences of the United States of America
Le VQ, Iacob RE, Tian Y, et al. (2018) Tolloid cleavage activates latent GDF8 by priming the pro-complex for dissociation. The Embo Journal
Nordenfelt P, Moore TI, Mehta SB, et al. (2017) Direction of actin flow dictates integrin LFA-1 orientation during leukocyte migration. Nature Communications. 8: 2047
Li J, Springer TA. (2017) Energy landscape differences among integrins establish the framework for understanding activation. The Journal of Cell Biology
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