Jeffrey R. Holt
Affiliations: | Harvard University, Cambridge, MA, United States |
Area:
sensory hair cellsWebsite:
https://sites.google.com/site/holtgeleoclab/peopleGoogle:
"Jeffrey Holt"Mean distance: 14 (cluster 6) | S | N | B | C | P |
Parents
Sign in to add mentor| Ruth Anne Eatock | grad student | 1991-1995 | Rochester |
| David P. Corey | post-doc | 1995-2001 | Harvard Medical School/ MGH |
Children
Sign in to add trainee| Michaela Levin | grad student | UVA | |
| Jessica R. Risner | grad student | 2002-2008 | UVA |
| Eric A. Stauffer | grad student | 2003-2008 | UVA |
| Geoffrey C. Horwitz | grad student | 2006-2012 | UVA |
| Ye-Hyun Kim | grad student | 2008-2014 | University of Virginia, Harvard |
| Charles Askew | grad student | 2008-2015 | University of Virginia, Harvard |
| Xiao Ping Liu | post-doc | Harvard |
BETA: Related publications
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Publications
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| Lee J, Kosuke Kawai K, Holt JR, et al. (2021) Sensory transduction is required for normal development and maturation ofcochlear inner hair cell synapses. Elife. 10 |
| Wu J, Solanes P, Nist-Lund C, et al. (2020) Single and dual vector gene therapy with AAV9-PHP.B rescues hearing in Tmc1 mutant mice. Molecular Therapy : the Journal of the American Society of Gene Therapy |
| Yeh WH, Shubina-Oleinik O, Levy JM, et al. (2020) In vivo base editing restores sensory transduction and transiently improves auditory function in a mouse model of recessive deafness. Science Translational Medicine. 12 |
| Lee J, Nist-Lund C, Solanes P, et al. (2020) Efficient viral transduction in mouse inner ear hair cells with utricle injection and AAV9-PHP.B. Hearing Research. 107882 |
| Meng X, Murali S, Cheng Y, et al. (2019) Increasing the Expression Level of ChR2 Enhances the Optogenetic Excitability of Cochlear Neurons. Journal of Neurophysiology |
| György B, Nist-Lund C, Pan B, et al. (2019) Allele-specific gene editing prevents deafness in a model of dominant progressive hearing loss. Nature Medicine |
| Nist-Lund CA, Pan B, Patterson A, et al. (2019) Publisher Correction: Improved TMC1 gene therapy restores hearing and balance in mice with genetic inner ear disorders. Nature Communications. 10: 734 |
| Nist-Lund CA, Pan B, Patterson A, et al. (2019) Improved TMC1 gene therapy restores hearing and balance in mice with genetic inner ear disorders. Nature Communications. 10: 236 |
| Holt JR, Geleoc GS. (2019) Split otoferlins reunited. Embo Molecular Medicine. 11 |
| Pan B, Akyuz N, Liu X, et al. (2019) Cysteine Substitution Reveals the Pore-Forming Region of TMC1 in Hair Cell Sensory Transduction Channels Biophysical Journal. 116: 460a |