Ronald J. Mandel

Affiliations: 
Neuroscience University of Florida, Gainesville, Gainesville, FL, United States 
Area:
Aging & Memory,Loss Gene Therapy, Neurological Disorders, Parkinson’s Disease,Huntington’s Disease, Dystonia
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"Ronald Mandel"
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Publications

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Koutzoumis DN, Vergara M, Pino J, et al. (2019) Alterations of the gut microbiota with antibiotics protects dopamine neuron loss and improve motor deficits in a pharmacological rodent model of Parkinson's disease. Experimental Neurology. 113159
Mandel RJ, Marmion DJ, Kirik D, et al. (2017) Novel oligodendroglial alpha synuclein viral vector models of multiple system atrophy: studies in rodents and nonhuman primates. Acta Neuropathologica Communications. 5: 47
Guadiana SM, Parker AK, Filho GF, et al. (2016) Type 3 Adenylyl Cyclase and Somatostatin Receptor 3 Expression Persists in Aged Rat Neocortical and Hippocampal Neuronal Cilia. Frontiers in Aging Neuroscience. 8: 127
Gombash SE, Manfredsson FP, Mandel RJ, et al. (2014) Neuroprotective potential of pleiotrophin overexpression in the striatonigral pathway compared with overexpression in both the striatonigral and nigrostriatal pathways. Gene Therapy. 21: 682-93
Oliveria SF, Foote KD, Mandel R. (2014) 192 Stereotactic Striatal Injection of a Regulated Glial Derived Neurotrophic Factor Expression System Neurosurgery. 61: 223-224
Manfredsson FP, Bloom DC, Mandel RJ. (2012) Regulated protein expression for in vivo gene therapy for neurological disorders: progress, strategies, and issues. Neurobiology of Disease. 48: 212-21
Gombash SE, Lipton JW, Collier TJ, et al. (2012) Striatal pleiotrophin overexpression provides functional and morphological neuroprotection in the 6-hydroxydopamine model. Molecular Therapy : the Journal of the American Society of Gene Therapy. 20: 544-54
Tebbenkamp AT, Green C, Xu G, et al. (2011) Transgenic mice expressing caspase-6-derived N-terminal fragments of mutant huntingtin develop neurologic abnormalities with predominant cytoplasmic inclusion pathology composed largely of a smaller proteolytic derivative. Human Molecular Genetics. 20: 2770-82
Manfredsson FP, Mandel RJ. (2011) The development of flexible lentiviral vectors for gene transfer in the CNS. Experimental Neurology. 229: 201-6
Mandel RJ, Lowenstein PR, Byrne BJ. (2011) AAV6-mediated gene silencing fALS short. Molecular Therapy : the Journal of the American Society of Gene Therapy. 19: 231-3
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