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Sampath K. Gollapudi, Ph.D.

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2011 Mechanical Engineering Washington State University, Pullman, WA, United States 
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David Lin grad student 2011 WSU
 (Modeling temperature dependent dynamic contractile properties in human skeletal muscle fibers using crossbridge models.)

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Ma W, Del Rio CL, Qi L, et al. (2024) Myosin in autoinhibited state(s), stabilized by mavacamten, can be recruited in response to inotropic interventions. Proceedings of the National Academy of Sciences of the United States of America. 121: e2314914121
Gollapudi SK, Ma W, Chakravarthy S, et al. (2021) Two Classes of Myosin Inhibitors, Para-nitroblebbistatin and Mavacamten, Stabilize β-Cardiac Myosin in Different Structural and Functional States. Journal of Molecular Biology. 433: 167295
Gollapudi SK, Sa N, Nag S. (2020) Decoupling the Interacting Head Motif and the Super Relaxed State of Myosin in Reconstituted Cardiac Bipolar Thick Filaments Biophysical Journal. 118: 423a
Ma W, Nag S, Chakravarthy S, et al. (2020) Effects of Mavacamten and Blebbistatin on the Small-Angle X-ray Scattering Structure of Human β-cardiac Myosin Biophysical Journal. 118: 422a
Reda SM, Gollapudi SK, Chandra M. (2019) Developmental increase in β-MHC enhances sarcomere length-dependent activation in the myocardium. The Journal of General Physiology
Sa N, Tomasic I, Gollapudi S, et al. (2019) Abstract 340: Myosin Regulatory Light Chain: A Major Player in Defining the ‘OFF’ State of Cardiac Myosin Circulation Research. 125
Sa N, Tomasic I, Gollapudi S, et al. (2018) Abstract 572: Role Of Human Cardiac RLC In Modulating The Super-relaxed State Of Myosin: A Cardiomyopathy Perspective Circulation Research. 123
Gollapudi SK, Reda SM, Chandra M. (2017) Omecamtiv Mecarbil Abolishes Length-Mediated Increase in Guinea Pig Cardiac Myofiber Ca(2+) Sensitivity. Biophysical Journal. 113: 880-888
Reda SM, Gollapudi SK, Chandra M. (2016) L71F mutation in rat cardiac troponin T augments crossbridge recruitment and detachment dynamics against α-myosin heavy chain, but not against β-myosin heavy chain. Journal of Muscle Research and Cell Motility
Mickelson AV, Gollapudi SK, Chandra M. (2016) Cardiomyopathy-related mutation (A30V) in mouse cardiac troponin T divergently alters the magnitude of stretch activation in α- and β-myosin heavy chain fibers. American Journal of Physiology. Heart and Circulatory Physiology. ajpheart.00487.2016
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