Danielle A. Simmons

Affiliations: 
Stanford University, Palo Alto, CA 
Area:
neuroinflammation, BDNF, Huntington's Disease
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"Danielle Simmons"
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Parents

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Judy Stern research assistant 1991-1995 Rutgers, New Brunswick
Pauline Yahr grad student 1996-2001 UC Irvine
 (Projections and neurotransmitters of cells activated with ejaculation.)
Frank Longo research scientist 2008- Stanford
Gary Lynch research scientist 2001-2008 UC Irvine
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Publications

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Simmons DA, Mills BD, Butler Iii RR, et al. (2021) Neuroimaging, Urinary, and Plasma Biomarkers of Treatment Response in Huntington's Disease: Preclinical Evidence with the p75 Ligand LM11A-31. Neurotherapeutics : the Journal of the American Society For Experimental Neurotherapeutics
Simmons DA, Lartey FM, Schüler E, et al. (2019) Reduced cognitive deficits after FLASH irradiation of whole mouse brain are associated with less hippocampal dendritic spine loss and neuroinflammation. Radiotherapy and Oncology : Journal of the European Society For Therapeutic Radiology and Oncology
Boakye PA, Rancic V, Whitlock KH, et al. (2019) Receptor-dependence of BDNF Actions in Superficial Dorsal Horn; Relation to Central Sensitization and Actions of Macrophage Colony Stimulating Factor 1 (CSF-1). Journal of Neurophysiology
Simmons DA, James ML, Belichenko NP, et al. (2018) TSPO-PET Imaging Using [18F]PBR06 is a Potential Translatable Biomarker for Treatment Response in Huntington's Disease: Preclinical Evidence with the p75NTR Ligand LM11A-31. Human Molecular Genetics
Simmons DA, Belichenko NP, Ford EC, et al. (2016) A small molecule p75NTR ligand normalizes signalling and reduces Huntington's disease phenotypes in R6/2 and BACHD mice. Human Molecular Genetics. 25: 4920-4938
Simmons DA, Longo FM, Massa SM. (2016) Neurotrophin receptor signaling as a therapeutic target for Huntington's Disease. Cns & Neurological Disorders Drug Targets
Simmons DA, Belichenko NP, Ford EC, et al. (2016) A small molecule p75NTR ligand normalizes signaling and reduces Huntington's Disease phenotypes in R6/2 and BACHD mice. Human Molecular Genetics
Yang T, Massa SM, Tran KC, et al. (2016) A small molecule TrkB/TrkC neurotrophin receptor co-activator with distinctive effects on neuronal survival and process outgrowth. Neuropharmacology
Simmons DA, Knowles JK, Belichenko NP, et al. (2014) A small molecule p75NTR ligand, LM11A-31, reverses cholinergic neurite dystrophy in Alzheimer's disease mouse models with mid- to late-stage disease progression. Plos One. 9: e102136
Villeda SA, Plambeck KE, Middeldorp J, et al. (2014) Young blood reverses age-related impairments in cognitive function and synaptic plasticity in mice. Nature Medicine. 20: 659-63
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