Jie Shen
Affiliations: | Harvard Medical School, Boston, MA, United States |
Area:
Molecular Basis of Alzheimer’s Disease and Parkinson’s DiseaseGoogle:
"Jie Shen"Mean distance: 21.07
Children
Sign in to add trainee| Randy S. Boyles | post-doc | Harvard Medical School - Brigham and Women's Hospital (FlyTree) |
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Publications
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| Lee SH, Kang J, Ho A, et al. (2020) APP Family Regulates Neuronal Excitability and Synaptic Plasticity but Not Neuronal Survival. Neuron |
| Dhaliwal J, Kannangara TS, Vaculik M, et al. (2018) Adult hippocampal neurogenesis occurs in the absence of Presenilin 1 and Presenilin 2. Scientific Reports. 8: 17931 |
| Parra-Damas A, Rubió-Ferrarons L, Shen J, et al. (2017) CRTC1 mediates preferential transcription at neuronal activity-regulated CRE/TATA promoters. Scientific Reports. 7: 18004 |
| Watanabe H, Shen J. (2017) Dominant negative mechanism of Presenilin-1 mutations in FAD. Proceedings of the National Academy of Sciences of the United States of America |
| Giaime E, Tong Y, Wagner LK, et al. (2017) Age-Dependent Dopaminergic Neurodegeneration and Impairment of the Autophagy-Lysosomal Pathway in LRRK-Deficient Mice. Neuron |
| Kelleher RJ, Shen J. (2017) Presenilin-1 mutations and Alzheimer's disease. Proceedings of the National Academy of Sciences of the United States of America |
| Xia D, Kelleher RJ, Shen J. (2016) Loss of Aβ43 Production Caused by Presenilin-1 Mutations in the Knockin Mouse Brain. Neuron. 90: 417-422 |
| Xia D, Watanabe H, Wu B, et al. (2015) Presenilin-1 knockin mice reveal loss-of-function mechanism for familial Alzheimer's disease. Neuron. 85: 967-81 |
| Watanabe H, Iqbal M, Zheng J, et al. (2014) Partial loss of presenilin impairs age-dependent neuronal survival in the cerebral cortex. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 34: 15912-22 |
| Grimm MO, Hundsdörfer B, Grösgen S, et al. (2014) PS dependent APP cleavage regulates glucosylceramide synthase and is affected in Alzheimer's disease. Cellular Physiology and Biochemistry : International Journal of Experimental Cellular Physiology, Biochemistry, and Pharmacology. 34: 92-110 |