David S. Thiriot, Ph.D.

Affiliations: 
2001 University of Wisconsin, Madison, Madison, WI 
Area:
Molecular mechanisms which underlie neurotransmitter release and receptor activation
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"David Thiriot"
Mean distance: 21373.2
 

Parents

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Arnold E Ruoho grad student 2001 UW Madison
 (Engineering the human vesicle monoamine transporter to study structure, function, and ligand binding sites.)
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Publications

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Lowery TJ, Wilson PE, Zhang B, et al. (2006) Flavodoxin hydroquinone reduces Azotobacter vinelandii Fe protein to the all-ferrous redox state with a S = 0 spin state. Proceedings of the National Academy of Sciences of the United States of America. 103: 17131-6
Thiriot DS, Nevzorov AA, Opella SJ. (2005) Structural basis of the temperature transition of Pf1 bacteriophage. Protein Science : a Publication of the Protein Society. 14: 1064-70
Thiriot DS, Nevzorov AA, Zagyanskiy L, et al. (2004) Structure of the coat protein in Pf1 bacteriophage determined by solid-state NMR spectroscopy. Journal of Molecular Biology. 341: 869-79
Mesleh MF, Lee S, Veglia G, et al. (2003) Dipolar waves map the structure and topology of helices in membrane proteins. Journal of the American Chemical Society. 125: 8928-35
Thiriot DS, Sievert MK, Ruoho AE. (2002) Identification of human vesicle monoamine transporter (VMAT2) lumenal cysteines that form an intramolecular disulfide bond. Biochemistry. 41: 6346-53
Thiriot DS, Ruoho AE. (2001) Mutagenesis and derivatization of human vesicle monoamine transporter 2 (VMAT2) cysteines identifies transporter domains involved in tetrabenazine binding and substrate transport. The Journal of Biological Chemistry. 276: 27304-15
Wu Z, Thiriot DS, Ruoho AE. (2001) Tyr199 in transmembrane domain 5 of the beta2-adrenergic receptor interacts directly with the pharmacophore of a unique fluorenone-based antagonist. The Biochemical Journal. 354: 485-91
Rong Y, Arbabian M, Thiriot DS, et al. (1999) Probing the salmeterol binding site on the beta 2-adrenergic receptor using a novel photoaffinity ligand, [(125)I]iodoazidosalmeterol. Biochemistry. 38: 11278-86
Sievert MK, Thiriot DS, Edwards RH, et al. (1998) High-efficiency expression and characterization of the synaptic-vesicle monoamine transporter from baculovirus-infected insect cells. The Biochemical Journal. 330: 959-66
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