Uyen B. Chu, Ph.D.

Affiliations: 
2011 University of Wisconsin, Madison, Madison, WI 
Area:
Molecular mechanisms which underlie neurotransmitter release and receptor activation
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"Uyen Chu"
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Parents

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Arnold E Ruoho grad student 2011 UW Madison
 (Synthesis and evaluation of novel N-alkylamine derivatives as high affinity sigma-1 receptor ligands.)
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Publications

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Chu UB, Ruoho AE. (2016) Biochemical Pharmacology of the Sigma-1 Receptor. Molecular Pharmacology. 89: 142-53
Chu UB, Mavlyutov TA, Chu ML, et al. (2015) The Sigma-2 Receptor and Progesterone Receptor Membrane Component 1 are Different Binding Sites Derived From Independent Genes. Ebiomedicine. 2: 1806-13
Chu UB, Ruoho AE. (2015) Sigma Receptor Binding Assays. Current Protocols in Pharmacology / Editorial Board, S.J. Enna (Editor-in-Chief) ... [Et Al.]. 71: 1.34.1-1.34.21
Gromek KA, Suchy FP, Meddaugh HR, et al. (2014) The oligomeric states of the purified sigma-1 receptor are stabilized by ligands Journal of Biological Chemistry. 289: 20333-20344
Chu UB, Vorperian SK, Satyshur K, et al. (2014) Noncompetitive inhibition of indolethylamine-N-methyltransferase by N,N-dimethyltryptamine and N,N-dimethylaminopropyltryptamine. Biochemistry. 53: 2956-65
Chu UB, Ramachandran S, Hajipour AR, et al. (2013) Photoaffinity labeling of the sigma-1 receptor with N-[3-(4-nitrophenyl)propyl]-N-dodecylamine: evidence of receptor dimers. Biochemistry. 52: 859-68
Ruoho AE, Chu UB, Ramachandran S, et al. (2012) The ligand binding region of the sigma-1 receptor: studies utilizing photoaffinity probes, sphingosine and N-alkylamines. Current Pharmaceutical Design. 18: 920-9
Chu UB, Hajipour AR, Ramachandran S, et al. (2011) Characterization of interactions of 4-nitrophenylpropyl-N-alkylamine with ς receptors. Biochemistry. 50: 7568-78
Hajipour AR, Fontanilla D, Chu UB, et al. (2010) Synthesis and characterization of N,N-dialkyl and N-alkyl-N-aralkyl fenpropimorph-derived compounds as high affinity ligands for sigma receptors. Bioorganic & Medicinal Chemistry. 18: 4397-404
Ramachandran S, Chu UB, Mavlyutov TA, et al. (2009) The sigma1 receptor interacts with N-alkyl amines and endogenous sphingolipids. European Journal of Pharmacology. 609: 19-26
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