James Trudell

Affiliations: 
Stanford University, Palo Alto, CA 
Area:
Anesthesia
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"James Trudell"
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Publications

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Borghese CM, Wang HL, McHardy SF, et al. (2021) Modulation of α1β3γ2 GABA receptors expressed in oocytes using a propofol photoswitch tethered to the transmembrane helix. Proceedings of the National Academy of Sciences of the United States of America. 118
Popova M, Rodriguez L, Trudell JR, et al. (2020) Residues in Transmembrane Segments of the P2X4 Receptor Contribute to Channel Function and Ethanol Sensitivity. International Journal of Molecular Sciences. 21
Pflanz NC, Daszkowski AW, Cornelison GL, et al. (2018) An intersubunit electrostatic interaction in the GABA receptor facilitates its responses to benzodiazepines. The Journal of Biological Chemistry. 293: 8264-8274
Borghese CM, Ruiz CI, Lee US, et al. (2015) Identification of an Inhibitory Alcohol Binding Site in GABAA ρ1 Receptors. Acs Chemical Neuroscience
Horani S, Stater EP, Corringer PJ, et al. (2015) Ethanol Modulation is Quantitatively Determined by the Transmembrane Domain of Human α1 Glycine Receptors. Alcoholism, Clinical and Experimental Research. 39: 962-8
Bertaccini EJ, Dickinson R, Trudell JR, et al. (2014) Molecular modeling of a tandem two pore domain potassium channel reveals a putative binding site for general anesthetics. Acs Chemical Neuroscience. 5: 1246-52
Naito A, Muchhala KH, Asatryan L, et al. (2014) Glycine and GABA(A) ultra-sensitive ethanol receptors as novel tools for alcohol and brain research. Molecular Pharmacology. 86: 635-46
Franklin KM, Asatryan L, Jakowec MW, et al. (2014) P2X4 receptors (P2X4Rs) represent a novel target for the development of drugs to prevent and/or treat alcohol use disorders. Frontiers in Neuroscience. 8: 176
Trudell JR, Messing RO, Mayfield J, et al. (2014) Alcohol dependence: molecular and behavioral evidence. Trends in Pharmacological Sciences. 35: 317-23
Howard RJ, Trudell JR, Harris RA. (2014) Seeking structural specificity: direct modulation of pentameric ligand-gated ion channels by alcohols and general anesthetics. Pharmacological Reviews. 66: 396-412
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