George Z. Mentis, Phd

Columbia University, New York, NY 
Neural Degeneration and Repair, Sensory Physiology, Synapses and Circuits, Motor Systems
"George Mentis"
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Fletcher EV, Simon CM, Pagiazitis JG, et al. (2017) Reduced sensory synaptic excitation impairs motor neuron function via Kv2.1 in spinal muscular atrophy. Nature Neuroscience
Remédio L, Gribble KD, Lee JK, et al. (2016) Diverging roles for Lrp4 and Wnt signaling in neuromuscular synapse development during evolution. Genes & Development. 30: 1058-69
Bikoff JB, Gabitto MI, Rivard AF, et al. (2016) Spinal Inhibitory Interneuron Diversity Delineates Variant Motor Microcircuits. Cell
Sharma A, Lyashchenko AK, Lu L, et al. (2016) ALS-associated mutant FUS induces selective motor neuron degeneration through toxic gain of function. Nature Communications. 7: 10465
Mendelsohn AI, Simon CM, Abbott LF, et al. (2015) Activity Regulates the Incidence of Heteronymous Sensory-Motor Connections. Neuron. 87: 111-23
de Nooij JC, Simon CM, Simon A, et al. (2015) The PDZ-domain protein Whirlin facilitates mechanosensory signaling in mammalian proprioceptors. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 35: 3073-84
Tisdale S, Lotti F, Saieva L, et al. (2013) SMN is essential for the biogenesis of U7 small nuclear ribonucleoprotein and 3'-end formation of histone mRNAs. Cell Reports. 5: 1187-95
Mentis GZ. (2012) The Spinal and Peripheral Motor System Fundamental Neuroscience: Fourth Edition. 613-630
Mentis GZ, Blivis D, Liu W, et al. (2011) Early functional impairment of sensory-motor connectivity in a mouse model of spinal muscular atrophy. Neuron. 69: 453-67
Siembab VC, Smith CA, Zagoraiou L, et al. (2010) Target selection of proprioceptive and motor axon synapses on neonatal V1-derived Ia inhibitory interneurons and Renshaw cells. The Journal of Comparative Neurology. 518: 4675-701
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