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Ross A. Cardarelli, PhD

Affiliations: 
2002-2006 University of Connecticut, Storrs, CT, United States 
 2006-2013 Neuroscience University of Maryland School of Medicine, Baltimore, MD, United States 
 2013-2019 Neuroscience Tufts University, Boston 
 2019- Caraway Therapeutics 
Area:
Electrophysiology, schizophrenia, dopamine, GABA, chloride homeostasis, epilepsy, neurodevelopmental/neurodegenerative disorders
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"Ross Cardarelli"
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Parents

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Patricio O'Donnell grad student 2007-2013 University of Maryland Medical School
 (Dominant-Negative Disrupted in Schizophrenia 1 Alters the Dopaminergic Modulation of Excitatory-Inhibitory Balance in the Prefrontal Cortex.)
Stephen J. Moss post-doc 2013-2017 Tufts

Children

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Publications

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Jarvis R, Josephine Ng SF, Nathanson AJ, et al. (2023) Direct activation of KCC2 arrests benzodiazepine refractory status epilepticus and limits the subsequent neuronal injury in mice. Cell Reports. Medicine. 100957
Kontou G, Josephine Ng SF, Cardarelli RA, et al. (2021) KCC2 is required for the survival of mature neurons but not for their development. The Journal of Biological Chemistry. 100364
Cardarelli RA, Martin R, Jaaro-Peled H, et al. (2018) Dominant-Negative DISC1 Alters the Dopaminergic Modulation of Inhibitory Interneurons in the Mouse Prefrontal Cortex. Molecular Neuropsychiatry. 4: 20-29
Kelley MR, Cardarelli RA, Smalley JL, et al. (2018) Locally Reducing KCC2 Activity in the Hippocampus is Sufficient to Induce Temporal Lobe Epilepsy. Ebiomedicine
Kelley MR, Cardarelli RA, Smalley JL, et al. (2018) Locally Reducing KCC2 Activity in the Hippocampus is Sufficient to Induce Temporal Lobe Epilepsy Ebiomedicine. 32: 62-71
Cardarelli RA, Jones K, Pisella LI, et al. (2017) The small molecule CLP257 does not modify activity of the K+-Cl- co-transporter KCC2 but does potentiate GABAA receptor activity. Nature Medicine. 23: 1394-1396
Agez M, Schultz P, Medina I, et al. (2017) Molecular architecture of potassium chloride co-transporter KCC2. Scientific Reports. 7: 16452
Agez M, Schultz P, Medina I, et al. (2017) Molecular architecture of potassium chloride co-transporter KCC2. Scientific Reports
Conway LC, Cardarelli RA, Moore YE, et al. (2017) N-ethylmaleimide increases KCC2 activity by modulating transporter phosphorylation. The Journal of Biological Chemistry
Conway LC, Cardarelli RA, Moore YE, et al. (2017) N-Ethylmaleimide increases KCC2 cotransporter activity by modulating transporter phosphorylation Journal of Biological Chemistry
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