Polyxeni Philippidou, Ph.D.

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2009 Stony Brook University, Stony Brook, NY, United States 
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"Polyxeni Philippidou"
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Simon Halegoua grad student 2009 SUNY Stony Brook
 (A specialized endosomal population mediates Trk, but not EGFR, retrograde signaling.)
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Publications

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Philippidou P, Dasen JS. (2015) Sensory-Motor Circuits: Hox Genes Get in Touch. Neuron. 88: 437-40
Philippidou P, Dasen JS. (2013) Hox genes: choreographers in neural development, architects of circuit organization. Neuron. 80: 12-34
Boucherat O, Montaron S, Bérubé-Simard FA, et al. (2013) Partial functional redundancy between Hoxa5 and Hoxb5 paralog genes during lung morphogenesis. American Journal of Physiology. Lung Cellular and Molecular Physiology. 304: L817-30
Lacombe J, Hanley O, Jung H, et al. (2013) Genetic and functional modularity of Hox activities in the specification of limb-innervating motor neurons. Plos Genetics. 9: e1003184
Philippidou P, Walsh CM, Aubin J, et al. (2012) Sustained Hox5 gene activity is required for respiratory motor neuron development. Nature Neuroscience. 15: 1636-44
Harrington AW, St Hillaire C, Zweifel LS, et al. (2011) Recruitment of actin modifiers to TrkA endosomes governs retrograde NGF signaling and survival. Cell. 146: 421-34
Philippidou P, Valdez G, Akmentin W, et al. (2011) Trk retrograde signaling requires persistent, Pincher-directed endosomes. Proceedings of the National Academy of Sciences of the United States of America. 108: 852-7
Schecterson LC, Hudson MP, Ko M, et al. (2010) Trk activation in the secretory pathway promotes Golgi fragmentation. Molecular and Cellular Neurosciences. 43: 403-13
Valdez G, Philippidou P, Rosenbaum J, et al. (2007) Trk-signaling endosomes are generated by Rac-dependent macroendocytosis. Proceedings of the National Academy of Sciences of the United States of America. 104: 12270-5
Boykevisch S, Zhao C, Sondermann H, et al. (2006) Regulation of Ras Signaling Dynamics by Sos-Mediated Positive Feedback Current Biology. 16: 2173-2179
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