Christopher R. Heier, Ph.D.

Affiliations: 
2010 Integrated Graduate Program in the Life Sciences Northwestern University, Evanston, IL 
Area:
Molecular Neuroscience, Motor Control, Neurobiology of Disease
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Parents

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Christine Didonato grad student 2010 Northwestern
 (Drug mechanisms targeting survival motor neuron gene expression benefit spinal muscular atrophy model mice.)
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Publications

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Spurney C, Panigrahi A, Heier C, et al. (2020) NOVEL SERUM PROTEIN BIOMARKERS SIGNIFICANTLY UP-REGULATED IN LGE NEGATIVE DMD SUBJECTS Journal of the American College of Cardiology. 75: 1061
Fiorillo AA, Heier CR, Novak JS, et al. (2015) TNF-α-Induced microRNAs Control Dystrophin Expression in Becker Muscular Dystrophy. Cell Reports. 12: 1678-90
Heier CR, DiDonato CJ. (2015) ECG in neonate mice with spinal muscular atrophy allows assessment of drug efficacy. Frontiers in Bioscience (Elite Edition). 7: 107-16
Dillingham BC, Knoblach SM, Many GM, et al. (2015) VBP15, a novel anti-inflammatory, is effective at reducing the severity of murine experimental autoimmune encephalomyelitis. Cellular and Molecular Neurobiology. 35: 377-87
Heier CR, Guerron AD, Korotcov A, et al. (2014) Non-invasive MRI and spectroscopy of mdx mice reveal temporal changes in dystrophic muscle imaging and in energy deficits. Plos One. 9: e112477
Heier CR, Damsker JM, Yu Q, et al. (2013) VBP15, a novel anti-inflammatory and membrane-stabilizer, improves muscular dystrophy without side effects. Embo Molecular Medicine. 5: 1569-85
Huynh T, Uaesoontrachoon K, Quinn JL, et al. (2013) Selective modulation through the glucocorticoid receptor ameliorates muscle pathology in mdx mice. The Journal of Pathology. 231: 223-35
Gogliotti RG, Cardona H, Singh J, et al. (2013) The DcpS inhibitor RG3039 improves survival, function and motor unit pathologies in two SMA mouse models. Human Molecular Genetics. 22: 4084-101
Damsker JM, Dillingham BC, Rose MC, et al. (2013) VBP15, a glucocorticoid analogue, is effective at reducing allergic lung inflammation in mice. Plos One. 8: e63871
Baudy AR, Reeves EK, Damsker JM, et al. (2012) Δ-9,11 modification of glucocorticoids dissociates nuclear factor-κB inhibitory efficacy from glucocorticoid response element-associated side effects. The Journal of Pharmacology and Experimental Therapeutics. 343: 225-32
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