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Ann H. Shim, Ph.D.

Affiliations: 
2011 Integrated Graduate Program in the Life Sciences Northwestern University, Evanston, IL 
Area:
Mechanisms of Drug Action, Molecular Neuroscience, Neurobiology of Disease, Signal Transduction
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"Ann Shim"
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Parents

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Xiaolin He grad student 2011 Northwestern
 (Structural Mechanisms in Class III Receptor Tyrosine Kinase Signaling.)
Murali Prakriya post-doc Amgen

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Publications

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Shim AH, Tirado-Lee L, Prakriya M. (2015) Structural and functional mechanisms of CRAC channel regulation. Journal of Molecular Biology. 427: 77-93
Shim AH, Chang RA, Chen X, et al. (2012) Multipronged attenuation of macrophage-colony stimulating factor signaling by Epstein-Barr virus BARF1. Proceedings of the National Academy of Sciences of the United States of America. 109: 12962-7
Liu H, Juo ZS, Shim AH, et al. (2010) Structural basis of semaphorin-plexin recognition and viral mimicry from Sema7A and A39R complexes with PlexinC1. Cell. 142: 749-61
Shim AH, Liu H, Focia PJ, et al. (2010) Structures of a platelet-derived growth factor/propeptide complex and a platelet-derived growth factor/receptor complex. Proceedings of the National Academy of Sciences of the United States of America. 107: 11307-12
Liu H, Shim AH, He X. (2009) Structural characterization of the ectodomain of a disintegrin and metalloproteinase-22 (ADAM22), a neural adhesion receptor instead of metalloproteinase: insights on ADAM function. The Journal of Biological Chemistry. 284: 29077-86
Chen X, Liu H, Focia PJ, et al. (2008) Structure of macrophage colony stimulating factor bound to FMS: diverse signaling assemblies of class III receptor tyrosine kinases. Proceedings of the National Academy of Sciences of the United States of America. 105: 18267-72
Chen X, Liu H, Shim AH, et al. (2008) Structural basis for synaptic adhesion mediated by neuroligin-neurexin interactions. Nature Structural & Molecular Biology. 15: 50-6
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