Katherine L. Neville, Ph.D.

2001 Northwestern University, Evanston, IL 
Molecular Neuroscience, Neurobiology of Disease, Neuroimmunology
"Katherine Neville"
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Stephen Miller grad student 2001 Northwestern
 (Integral role of autoreactive cells in the progression of TMEV-IDD: Regulation of disease by CD28 costimulatory blockade and myelin -specific tolerance.)
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Mack CL, Vanderlugt-Castaneda CL, Neville KL, et al. (2003) Microglia are activated to become competent antigen presenting and effector cells in the inflammatory environment of the Theiler's virus model of multiple sclerosis. Journal of Neuroimmunology. 144: 68-79
Howard LM, Neville KL, Haynes LM, et al. (2003) CD154 blockade results in transient reduction in Theiler's murine encephalomyelitis virus-induced demyelinating disease. Journal of Virology. 77: 2247-50
Neville KL, Padilla J, Miller SD. (2002) Myelin-specific tolerance attenuates the progression of a virus-induced demyelinating disease: implications for the treatment of MS. Journal of Neuroimmunology. 123: 18-29
Begolka WS, Haynes LM, Olson JK, et al. (2001) CD8-deficient SJL mice display enhanced susceptibility to Theiler's virus infection and increased demyelinating pathology. Journal of Neurovirology. 7: 409-20
Miller SD, Katz-Levy Y, Neville KL, et al. (2001) Virus-induced autoimmunity: epitope spreading to myelin autoepitopes in Theiler's virus infection of the central nervous system. Advances in Virus Research. 56: 199-217
Katz-Levy Y, Neville KL, Padilla J, et al. (2000) Temporal development of autoreactive Th1 responses and endogenous presentation of self myelin epitopes by central nervous system-resident APCs in Theiler's virus-infected mice. Journal of Immunology (Baltimore, Md. : 1950). 165: 5304-14
Neville KL, Dal Canto MC, Bluestone JA, et al. (2000) CD28 costimulatory blockade exacerbates disease severity and accelerates epitope spreading in a virus-induced autoimmune disease. Journal of Virology. 74: 8349-57
Vanderlugt CL, Neville KL, Nikcevich KM, et al. (2000) Pathologic role and temporal appearance of newly emerging autoepitopes in relapsing experimental autoimmune encephalomyelitis. Journal of Immunology (Baltimore, Md. : 1950). 164: 670-8
Katz-Levy Y, Neville KL, Girvin AM, et al. (1999) Endogenous presentation of self myelin epitopes by CNS-resident APCs in Theiler's virus-infected mice. The Journal of Clinical Investigation. 104: 599-610
Vanderlugt CL, Begolka WS, Neville KL, et al. (1998) The functional significance of epitope spreading and its regulation by co-stimulatory molecules. Immunological Reviews. 164: 63-72
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