Kay Elizabeth Davies

Affiliations: 
University of Oxford, Oxford, United Kingdom 
Area:
Muscular Dystrophy, Ataxia
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"Kay Davies"
Mean distance: 17.02 (cluster 28)
 

Children

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Benjamin Edwards research assistant Oxford
Ruben J. Cauchi grad student Malta
William T. Clarke grad student Oxford
Olivia Osborn grad student Scripps Institute
Kenny Roberts grad student Oxford
Anna Dulneva grad student 2008- Oxford
Kevin Talbot grad student 1998 Oxford
Joanne Clark grad student 2002-2006 Oxford
Simon D'Alton grad student 2005-2008 Oxford
Mattéa J. Finelli grad student 2007-2010 Oxford
James Nicholas Sleigh grad student 2009-2012 Oxford
Kevin X. Liu grad student 2011-2014 Oxford
Emmanuelle Bitoun post-doc Oxford
Rebecca J. Fairclough post-doc Oxford
Peter L. Oliver post-doc Oxford
Esther B E Becker post-doc 2006-2010 Oxford

Collaborators

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Simon E. Fisher collaborator Oxford
Zoltan Molnar collaborator Oxford
Kevin Talbot collaborator Oxford
BETA: Related publications

Publications

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Vuorinen A, Wilkinson IVL, Chatzopoulou M, et al. (2021) Discovery and mechanism of action studies of 4,6-diphenylpyrimidine-2-carbohydrazides as utrophin modulators for the treatment of Duchenne muscular dystrophy. European Journal of Medicinal Chemistry. 220: 113431
Chatzopoulou M, Emer E, Lecci C, et al. (2020) Decreasing HepG2 Cytotoxicity by Lowering the Lipophilicity of Benzo[d]oxazolephosphinate Ester Utrophin Modulators. Acs Medicinal Chemistry Letters. 11: 2421-2427
Lovering RM, Iyer SR, Edwards B, et al. (2020) Alterations of neuromuscular junctions in Duchenne muscular dystrophy. Neuroscience Letters. 135304
Babbs A, Berg A, Chatzopoulou M, et al. (2020) Synthesis of SMT022357 enantiomers and evaluation in a Duchenne muscular dystrophy mouse model. Tetrahedron. 76: 130819
Babbs A, Berg A, Chatzopoulou M, et al. (2020) 2-Arylbenzo[d]oxazole phosphinate esters as second-generation modulators of utrophin for the treatment of Duchenne Muscular Dystrophy. Journal of Medicinal Chemistry
Wilkinson IVL, Perkins KJ, Dugdale H, et al. (2019) Chemical Proteomics and Phenotypic Profiling Identifies the Aryl Hydrocarbon Receptor as a Molecular Target of the Utrophin Modulator Ezutromid. Angewandte Chemie (International Ed. in English)
Williamson MG, Finelli MJ, Sleigh JN, et al. (2019) Neuronal over-expression of Oxr1 is protective against ALS-associated mutant TDP-43 mislocalisation in motor neurons and neuromuscular defects in vivo. Human Molecular Genetics
Chatzopoulou M, Claridge TDW, Davies KE, et al. (2019) Isolation, structural identification, synthesis, and pharmacological profiling of 1,2-trans-dihydro-1,2-diol metabolites of the utrophin modulator ezutromid. Journal of Medicinal Chemistry
Pomatto LCD, Sun PY, Yu K, et al. (2019) Limitations to adaptive homeostasis in an hyperoxia-induced model of accelerated ageing. Redox Biology. 24: 101194
Guiraud S, Edwards B, Babbs A, et al. (2019) The potential of utrophin and dystrophin combination therapies for Duchenne muscular dystrophy. Human Molecular Genetics
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