Karl H. Weisgraber

Gladstone Institute, UCSF, San Francisco, CA, United States 
apolipoprotein E
"Karl Weisgraber"
Mean distance: 16.69 (cluster 11)
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Adeosun SO, Hou X, Zheng B, et al. (2014) Cognitive deficits and disruption of neurogenesis in a mouse model of apolipoprotein E4 domain interaction. The Journal of Biological Chemistry. 289: 2946-59
Zhang L, Yan F, Zhang S, et al. (2012) Structural basis of transfer between lipoproteins by cholesteryl ester transfer protein. Nature Chemical Biology. 8: 342-9
Peters-Libeu C, Miller J, Rutenber E, et al. (2012) Disease-associated polyglutamine stretches in monomeric huntingtin adopt a compact structure. Journal of Molecular Biology. 421: 587-600
Chen HK, Liu Z, Meyer-Franke A, et al. (2012) Small molecule structure correctors abolish detrimental effects of apolipoprotein E4 in cultured neurons. The Journal of Biological Chemistry. 287: 5253-66
Miller J, Arrasate M, Brooks E, et al. (2011) Identifying polyglutamine protein species in situ that best predict neurodegeneration. Nature Chemical Biology. 7: 925-34
Brodbeck J, McGuire J, Liu Z, et al. (2011) Structure-dependent impairment of intracellular apolipoprotein E4 trafficking and its detrimental effects are rescued by small-molecule structure correctors. The Journal of Biological Chemistry. 286: 17217-26
Chen HK, Ji ZS, Dodson SE, et al. (2011) Apolipoprotein E4 domain interaction mediates detrimental effects on mitochondria and is a potential therapeutic target for Alzheimer disease. The Journal of Biological Chemistry. 286: 5215-21
Zhang L, Song J, Cavigiolio G, et al. (2011) Morphology and structure of lipoproteins revealed by an optimized negative-staining protocol of electron microscopy. Journal of Lipid Research. 52: 175-84
Newhouse Y, Weisgraber KH. (2011) Apolipoprotein E expression and purification. Methods in Molecular Biology (Clifton, N.J.). 670: 127-40
Zhang L, Song J, Newhouse Y, et al. (2010) An optimized negative-staining protocol of electron microscopy for apoE4 POPC lipoprotein. Journal of Lipid Research. 51: 1228-36
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