Paola Sacchetti, Ph.D.
Affiliations: | Biology | Mount Holyoke College, South Hadley, MA |
Area:
Parkinson's disease, nuclear receptorsWebsite:
http://www.mtholyoke.edu/acad/biologicalsciences/paola_sacchetti.htmlGoogle:
"Paola Sacchetti"Mean distance: 14.85 (cluster 11) | S | N | B | C | P |
Parents
Sign in to add mentor| Michael J. Bannon | grad student | 1996-2000 | Wayne State | |
| (Positive and negative elements affecting the transcriptional expression of the human dopamine transporter gene.) | ||||
| Philippe Lefebvre | post-doc | 2000-2005 | INSERM | |
| Ernest Arenas | post-doc | 2005-2009 | Karolinska | |
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Publications
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| Theofilopoulos S, Wang Y, Kitambi SS, et al. (2013) Brain endogenous liver X receptor ligands selectively promote midbrain neurogenesis. Nature Chemical Biology. 9: 126-33 |
| Theofilopoulos S, Karu K, Kitambi S, et al. (2011) Identification and characterisation of endogenous LXR ligands in ventral midbrain development Neuroscience Research. 71: e50 |
| Sacchetti P, Sousa KM, Hall AC, et al. (2009) Liver X receptors and oxysterols promote ventral midbrain neurogenesis in vivo and in human embryonic stem cells. Cell Stem Cell. 5: 409-19 |
| Rawal N, Corti O, Sacchetti P, et al. (2009) Parkin protects dopaminergic neurons from excessive Wnt/beta-catenin signaling. Biochemical and Biophysical Research Communications. 388: 473-8 |
| Wang Y, Sousa KM, Bodin K, et al. (2009) Targeted lipidomic analysis of oxysterols in the embryonic central nervous system. Molecular Biosystems. 5: 529-41 |
| Andersson T, Södersten E, Duckworth JK, et al. (2009) CXXC5 is a novel BMP4-regulated modulator of Wnt signaling in neural stem cells. The Journal of Biological Chemistry. 284: 3672-81 |
| Carpentier R, Sacchetti P, Ségard P, et al. (2008) The glucocorticoid receptor is a co-regulator of the orphan nuclear receptor Nurr1. Journal of Neurochemistry. 104: 777-89 |
| Sacchetti P, Carpentier R, Ségard P, et al. (2006) Multiple signaling pathways regulate the transcriptional activity of the orphan nuclear receptor NURR1. Nucleic Acids Research. 34: 5515-27 |
| Jouault T, Ibata-Ombetta S, Takeuchi O, et al. (2003) Candida albicans phospholipomannan is sensed through toll-like receptors. The Journal of Infectious Diseases. 188: 165-72 |
| Sacchetti P, Dwornik H, Formstecher P, et al. (2002) Requirements for heterodimerization between the orphan nuclear receptor Nurr1 and retinoid X receptors. The Journal of Biological Chemistry. 277: 35088-96 |