Hsue-Cheng Chiang
Affiliations: | Cold Spring Harbor Laboratory, Cold Spring Harbor, NY |
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"Hsue-Cheng Chiang"Mean distance: 16.97 (cluster 11) | S | N | B | C | P |
Parents
Sign in to add mentor| Huaibin Cai | research assistant | NIH | ||
| Yi Zhong | grad student | 2009 | SUNY Stony Brook | |
| (Drosophila model of Alzheimer's disease.) | ||||
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Publications
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| Wang L, Chiang HC, Wu W, et al. (2012) Epidermal growth factor receptor is a preferred target for treating amyloid-β-induced memory loss. Proceedings of the National Academy of Sciences of the United States of America. 109: 16743-8 |
| Chiang HC, Wang L, Xie Z, et al. (2010) PI3 kinase signaling is involved in Abeta-induced memory loss in Drosophila. Proceedings of the National Academy of Sciences of the United States of America. 107: 7060-5 |
| Chiang HC, Iijima K, Hakker I, et al. (2009) Distinctive roles of different beta-amyloid 42 aggregates in modulation of synaptic functions. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 23: 1969-77 |
| Iijima-Ando K, Hearn SA, Granger L, et al. (2008) Overexpression of neprilysin reduces alzheimer amyloid-beta42 (Abeta42)-induced neuron loss and intraneuronal Abeta42 deposits but causes a reduction in cAMP-responsive element-binding protein-mediated transcription, age-dependent axon pathology, and premature death in Drosophila. The Journal of Biological Chemistry. 283: 19066-76 |
| Iijima K, Chiang HC, Hearn SA, et al. (2008) Abeta42 mutants with different aggregation profiles induce distinct pathologies in Drosophila. Plos One. 3: e1703 |
| Lai C, Xie C, McCormack SG, et al. (2006) Amyotrophic lateral sclerosis 2-deficiency leads to neuronal degeneration in amyotrophic lateral sclerosis through altered AMPA receptor trafficking. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 11798-806 |
| Laird FM, Cai H, Savonenko AV, et al. (2005) BACE1, a major determinant of selective vulnerability of the brain to amyloid-beta amyloidogenesis, is essential for cognitive, emotional, and synaptic functions. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 25: 11693-709 |
| Cai H, Lin X, Xie C, et al. (2005) Loss of ALS2 function is insufficient to trigger motor neuron degeneration in knock-out mice but predisposes neurons to oxidative stress. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 25: 7567-74 |