Danhui Zhang, Ph.D.

Affiliations: 
2008 Biomedical Sciences Iowa State University, Ames, IA, United States 
Area:
Neuroscience, Toxicology
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"Danhui Zhang"
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Anumantha G. Kanthasamy grad student 2008 Iowa State
 (Protein Kinase C-delta in dopaminergic system and experimental models of Parkinson's disease.)
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Publications

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Saminathan H, Ghosh A, Zhang D, et al. (2021) Fyn Kinase-Mediated PKCδ Y311 Phosphorylation Induces Dopaminergic Degeneration in Cell Culture and Animal Models: Implications for the Identification of a New Pharmacological Target for Parkinson's Disease. Frontiers in Pharmacology. 12: 631375
Klionsky DJ, Abdelmohsen K, Abe A, et al. (2016) Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition). Autophagy. 12: 1-222
Zhao M, Ren H, Chang J, et al. (2016) Design and synthesis of novel pyrazolo[1,5-a]pyrimidine derivatives bearing nitrogen mustard moiety and evaluation of their antitumor activity in vitro and in vivo European Journal of Medicinal Chemistry. 119: 183-196
Zhang H, Luo X, Ke J, et al. (2016) Procyanidins, from Castanea mollissima Bl. shell, induces autophagy following apoptosis associated with PI3K/AKT/mTOR inhibition in HepG2 cells Biomedicine and Pharmacotherapy. 81: 15-24
Zhang D, Kanthasamy A, Anantharam V, et al. (2011) Effects of manganese on tyrosine hydroxylase (TH) activity and TH-phosphorylation in a dopaminergic neural cell line. Toxicology and Applied Pharmacology. 254: 65-71
Sun F, Anantharam V, Jin H, et al. (2008) Neuroprotective and Neurotoxic Properties of α-Synuclein in Cell Culture Models of Dopaminergic Degeneration Parkinson's Disease. 475-490
Zhang D, Anantharam V, Kanthasamy A, et al. (2007) Neuroprotective effect of protein kinase C delta inhibitor rottlerin in cell culture and animal models of Parkinson's disease. The Journal of Pharmacology and Experimental Therapeutics. 322: 913-22
Zhang D, Kanthasamy A, Yang Y, et al. (2007) Protein kinase C delta negatively regulates tyrosine hydroxylase activity and dopamine synthesis by enhancing protein phosphatase-2A activity in dopaminergic neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 5349-62
Kanthasamy AG, Anantharam V, Zhang D, et al. (2006) A novel peptide inhibitor targeted to caspase-3 cleavage site of a proapoptotic kinase protein kinase C delta (PKCdelta) protects against dopaminergic neuronal degeneration in Parkinson's disease models. Free Radical Biology & Medicine. 41: 1578-89
Sun F, Anantharam V, Zhang D, et al. (2006) Proteasome inhibitor MG-132 induces dopaminergic degeneration in cell culture and animal models. Neurotoxicology. 27: 807-15
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