Hariharan Saminathan, Ph.D.
Affiliations: | 2011 | Interdisciplinary Graduate Studies | Iowa State University, Ames, IA, United States |
Area:
Neuroscience, ToxicologyGoogle:
"Hariharan Saminathan"Mean distance: 13358.2
Parents
Sign in to add mentorAnumantha G. Kanthasamy | grad student | 2011 | Iowa State | |
(Role of Fyn kinase in dopaminergic neuronal degeneration: Relevance to oxidative damage in Parkinson's disease.) |
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Publications
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Johnson AM, Jose S, Palakkott AR, et al. (2023) Pharmacological Inhibition of PTEN Rescues Dopaminergic Neurons by Attenuating Apoptotic and Neuroinflammatory Signaling Events. Journal of Neuroimmune Pharmacology : the Official Journal of the Society On Neuroimmune Pharmacology |
Johnson AM, Ou ZA, Gordon R, et al. (2021) Environmental neurotoxicants and inflammasome activation in Parkinson's disease - a focus on the gut-brain axis. The International Journal of Biochemistry & Cell Biology. 106113 |
Saminathan H, Ghosh A, Zhang D, et al. (2021) Fyn Kinase-Mediated PKCδ Y311 Phosphorylation Induces Dopaminergic Degeneration in Cell Culture and Animal Models: Implications for the Identification of a New Pharmacological Target for Parkinson's Disease. Frontiers in Pharmacology. 12: 631375 |
Saminathan H, Charli A, Luo J, et al. (2020) Fyn kinase mediates pro-inflammatory response in a mouse model of endotoxemia: Relevance to translational research. European Journal of Pharmacology. 173259 |
Panicker N, Sarkar S, Harischandra DS, et al. (2019) Fyn kinase regulates misfolded α-synuclein uptake and NLRP3 inflammasome activation in microglia. The Journal of Experimental Medicine |
Panicker N, Saminathan H, Jin H, et al. (2015) Fyn Kinase Regulates Microglial Neuroinflammatory Responses in Cell Culture and Animal Models of Parkinson's Disease. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 35: 10058-77 |
Ghosh A, Saminathan H, Kanthasamy A, et al. (2013) The peptidyl-prolyl isomerase Pin1 up-regulation and proapoptotic function in dopaminergic neurons: relevance to the pathogenesis of Parkinson disease. The Journal of Biological Chemistry. 288: 21955-71 |
Saminathan H, Asaithambi A, Anantharam V, et al. (2011) Environmental neurotoxic pesticide dieldrin activates a non receptor tyrosine kinase to promote PKCδ-mediated dopaminergic apoptosis in a dopaminergic neuronal cell model. Neurotoxicology. 32: 567-77 |
Asaithambi A, Kanthasamy A, Saminathan H, et al. (2011) Protein kinase D1 (PKD1) activation mediates a compensatory protective response during early stages of oxidative stress-induced neuronal degeneration. Molecular Neurodegeneration. 6: 43 |