Lucas R. Smith, Ph.D.

Affiliations: 
2011 Bioengineering University of California, San Diego, La Jolla, CA 
Area:
Biomedical
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"Lucas Smith"

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Richard L. Lieber grad student 2011 UCSD
 (Skeletal muscle adaptations in hamstring contractures of children with cerebral palsy.)
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Publications

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Johnson N, Filler AC, Sethi A, et al. (2023) Skeletal Muscle Spheroids as Building Blocks for Engineered Muscle Tissue. Acs Biomaterials Science & Engineering
Wohlgemuth RP, Brashear SE, Smith LR. (2023) Alignment, cross-linking, and beyond: A collagen architect's guide to the skeletal muscle extracellular matrix. American Journal of Physiology. Cell Physiology
Loomis T, Smith LR. (2023) Thrown for a Loop: Fibro-Adipogenic Progenitors in Skeletal Muscle Fibrosis. American Journal of Physiology. Cell Physiology
Wohlgemuth RP, Feitzinger RM, Henricson KE, et al. (2023) The extracellular matrix of dystrophic mouse diaphragm accounts for the majority of its passive stiffness and is resistant to collagenase digestion. Matrix Biology Plus. 18: 100131
Gionet-Gonzales MA, Gresham RCH, Griffin KH, et al. (2022) Mesenchymal stromal cell spheroids in sulfated alginate enhance muscle regeneration. Acta Biomaterialia
Brashear SE, Wohlgemuth RP, Hu LY, et al. (2022) Collagen cross-links scale with passive stiffness in dystrophic mouse muscles, but are not altered with administration of a lysyl oxidase inhibitor. Plos One. 17: e0271776
Ritter P, Nübler S, Buttgereit A, et al. (2022) Myofibrillar Lattice Remodeling Is a Structural Cytoskeletal Predictor of Diaphragm Muscle Weakness in a Fibrotic () Model. International Journal of Molecular Sciences. 23
Loomis T, Hu LY, Wohlgemuth RP, et al. (2022) Matrix stiffness and architecture drive fibro-adipogenic progenitors' activation into myofibroblasts. Scientific Reports. 12: 13582
Hu LY, Mileti CJ, Loomis T, et al. (2021) Skeletal Muscle progenitors are sensitive to collagen architectural features of fibril size and crosslinking. American Journal of Physiology. Cell Physiology
Brashear SE, Wohlgemuth RP, Gonzalez G, et al. (2020) Passive stiffness of fibrotic skeletal muscle in mdx mice relates to collagen architecture. The Journal of Physiology
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