Barbara A. Spruce

University of Dundee, Dundee, Scotland, United Kingdom 
Enkephalins, astrocytes, molecular endocrinology
"Barbara Spruce"
Mean distance: 106866
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McTavish N, Copeland LA, Saville MK, et al. (2007) Proenkephalin assists stress-activated apoptosis through transcriptional repression of NF-kappaB- and p53-regulated gene targets. Cell Death and Differentiation. 14: 1700-10
Achison M, Boylan MT, Hupp TR, et al. (2007) HIF-1alpha contributes to tumour-selective killing by the sigma receptor antagonist rimcazole. Oncogene. 26: 1137-46
Wang L, Prescott AR, Spruce BA, et al. (2005) Sigma receptor antagonists inhibit human lens cell growth and induce pigmentation. Investigative Ophthalmology & Visual Science. 46: 1403-8
Spruce BA, Campbell LA, McTavish N, et al. (2004) Small molecule antagonists of the sigma-1 receptor cause selective release of the death program in tumor and self-reliant cells and inhibit tumor growth in vitro and in vivo. Cancer Research. 64: 4875-86
Wiegand UK, Corbach S, Prescott AR, et al. (2001) The trigger to cell death determines the efficiency with which dying cells are cleared by neighbours. Cell Death and Differentiation. 8: 734-46
Knapp PE, Itkis OS, Zhang L, et al. (2001) Angiotensin receptor-like immunoreactivity in adult brain white matter astrocytes and oligodendrocytes Glia. 35: 131-146
Devvar DA, Spraggon C, Midgeley C, et al. (1996) Nuclear proenkephalin induces cell death in a P53 dose-dependent manner Biochemical Society Transactions. 24: 571S
Böttger A, Spruce BA. (1995) Proenkephalin is a nuclear protein responsive to growth arrest and differentiation signals. The Journal of Cell Biology. 130: 1251-62
Böttger V, Böttger A, Lane EB, et al. (1995) Comprehensive epitope analysis of monoclonal anti-proenkephalin antibodies using phage display libraries and synthetic peptides: revelation of antibody fine specificities caused by somatic mutations in the variable region genes. Journal of Molecular Biology. 247: 932-46
Osborne JG, Kindy MS, Spruce BA, et al. (1993) Ontogeny of proenkephalin mRNA and enkephalin peptide expression in the cerebellar cortex of the rat: spatial and temporal patterns of expression follow maturational gradients in the external granular layer and in Purkinje cells. Brain Research. Developmental Brain Research. 76: 1-12
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