Trevor Stitt

Regeneron, Rensselaer, NY, United States

neurotrophins, tyrosine kinase receptors, muscle

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Latres E, Mastaitis J, Fury W, et al. (2017) Activin A more prominently regulates muscle mass in primates than does GDF8. Nature Communications. 8: 15153
Latres E, Pangilinan J, Miloscio L, et al. (2015) Myostatin blockade with a fully human monoclonal antibody induces muscle hypertrophy and reverses muscle atrophy in young and aged mice. Skeletal Muscle. 5: 34
Lai KM, Gonzalez M, Poueymirou WT, et al. (2004) Conditional activation of akt in adult skeletal muscle induces rapid hypertrophy. Molecular and Cellular Biology. 24: 9295-304
Stitt TN, Drujan D, Clarke BA, et al. (2004) The IGF-1/PI3K/Akt pathway prevents expression of muscle atrophy-induced ubiquitin ligases by inhibiting FOXO transcription factors. Molecular Cell. 14: 395-403
Valenzuela DM, Stitt TN, DiStefano PS, et al. (1995) Receptor tyrosine kinase specific for the skeletal muscle lineage: expression in embryonic muscle, at the neuromuscular junction, and after injury. Neuron. 15: 573-84