Andrew J. Mannes

DASS, Clinical Center, NIH, Bethesda, MD, United States 
Neurobiology of Pain and Pain Control
"Andrew Mannes"

Andrew J. Mannes, M.D. is an active anesthesiologist. His research interests are in novel treatments for pain and include gene therapy for pain, cell deletion approaches to pain control using resiniferatoxin and protein therapeutic agents.

Mean distance: 16.66 (cluster 11)
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Sapio MR, Iadarola MJ, LaPaglia DM, et al. (2019) Haploinsufficiency of the brain-derived neurotrophic factor (BDNF) gene is associated with reduced pain sensitivity. Pain
Yuan ZX, Majchrzak-Hong S, Keyes GS, et al. (2018) Lipidomic profiling of targeted oxylipins with ultra-performance liquid chromatography-tandem mass spectrometry. Analytical and Bioanalytical Chemistry
Iadarola MJ, Sapio MR, Raithel SJ, et al. (2018) Long-term pain relief in canine osteoarthritis by a single intra-articular injection of resiniferatoxin, a potent TRPV1 agonist. Pain
Sapio MR, Neubert JK, LaPaglia DM, et al. (2018) Pain control through selective chemo-axotomy of centrally projecting TRPV1+ sensory neurons. The Journal of Clinical Investigation
Hall BE, Prochazkova M, Sapio MR, et al. (2018) Phosphorylation of the Transient Receptor Potential Ankyrin 1 by Cyclin-dependent Kinase 5 affects Chemo-nociception. Scientific Reports. 8: 1177
Raithel SJ, Sapio MR, LaPaglia DM, et al. (2017) Transcriptional Changes in Dorsal Spinal Cord Persist after Surgical Incision Despite Preemptive Analgesia with Peripheral Resiniferatoxin. Anesthesiology
Raithel SJ, Sapio MR, Iadarola MJ, et al. (2017) Thermal A-δ Nociceptors, Identified by Transcriptomics, Express Higher Levels of Anesthesia-Sensitive Receptors Than Thermal C-Fibers and Are More Suppressible by Low-Dose Isoflurane. Anesthesia and Analgesia
Ramsden CE, Domenichiello AF, Yuan ZX, et al. (2017) A systems approach for discovering linoleic acid derivatives that potentially mediate pain and itch. Science Signaling. 10
Iadarola MJ, Sapio MR, Wang X, et al. (2017) [EXPRESS]Analgesia by Deletion of Spinal Neurokinin 1 Receptor Expressing Neurons Using a Bioengineered Substance P-Pseudomonas Exotoxin Conjugate. Molecular Pain. 13: 1744806917727657
LaPaglia DM, Sapio MR, Burbelo PD, et al. (2017) RNA-Seq investigations of human post-mortem trigeminal ganglia. Cephalalgia : An International Journal of Headache. 333102417720216
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