Anne Need, Ph.D.
Affiliations: | 2008 | Medical Neurobiology | Indiana University, Bloomington, Bloomington, IN, United States |
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Neuroscience BiologyGoogle:
"Anne Need"Mean distance: 42746.4
Parents
Sign in to add mentor| Jay R. Simon | grad student | 2008 | Indiana University | |
| (Development and characterization of a methodology for the simultaneous and individual determination of in vivo receptor occupancy at mu, delta, and kappa opioid receptors, and examination of the effects of opioid antagonist occupancy on feeding behavior i) | ||||
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Publications
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| Knopp KL, Simmons RMA, Guo W, et al. (2019) Modulation of TARP γ8-containing AMPA Receptors as a Novel Therapeutic Approach for Chronic Pain. The Journal of Pharmacology and Experimental Therapeutics |
| Gardinier KM, Gernert DL, Porter WJ, et al. (2016) The Discovery of The First α-Amino-3-Hydroxy-5-Methyl-4-Isoxazolepropionic Acid (AMPA) Receptor Antagonist Dependent Upon Transmembrane AMPA Receptor Regulatory Protein (TARP) Gamma-8. Journal of Medicinal Chemistry |
| Rorick-Kehn LM, Witcher JW, Lowe SL, et al. (2014) Determining pharmacological selectivity of the kappa opioid receptor antagonist LY2456302 using pupillometry as a translational biomarker in rat and human. The International Journal of Neuropsychopharmacology / Official Scientific Journal of the Collegium Internationale Neuropsychopharmacologicum (Cinp). 18 |
| Joshi EM, Need A, Schaus J, et al. (2014) Efficiency gains in tracer identification for nuclear imaging: can in vivo LC-MS/MS evaluation of small molecules screen for successful PET tracers? Acs Chemical Neuroscience. 5: 1154-63 |
| Zheng MQ, Kim SJ, Holden D, et al. (2014) An Improved Antagonist Radiotracer for the κ-Opioid Receptor: Synthesis and Characterization of (11)C-LY2459989. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. 55: 1185-91 |
| Barth V, Need A. (2014) Identifying novel radiotracers for PET imaging of the brain: application of LC-MS/MS to tracer identification. Acs Chemical Neuroscience. 5: 1148-53 |
| Need AB, McKinzie JH, Mitch CH, et al. (2007) In vivo rat brain opioid receptor binding of LY255582 assessed with a novel method using LC/MS/MS and the administration of three tracers simultaneously. Life Sciences. 81: 1389-96 |
| Li X, Need AB, Baez M, et al. (2006) Metabotropic glutamate 5 receptor antagonism is associated with antidepressant-like effects in mice. The Journal of Pharmacology and Experimental Therapeutics. 319: 254-9 |
| Barth VN, Chernet E, Martin LJ, et al. (2006) Comparison of rat dopamine D2 receptor occupancy for a series of antipsychotic drugs measured using radiolabeled or nonlabeled raclopride tracer. Life Sciences. 78: 3007-12 |
| Need AB, Davis RJ, Alexander-Chacko JT, et al. (2006) The relationship of in vivo central CB1 receptor occupancy to changes in cortical monoamine release and feeding elicited by CB1 receptor antagonists in rats. Psychopharmacology. 184: 26-35 |