Leigh A. Needleman
Affiliations: | Harvard University, HHMI, Cambridge, MA, United States |
Area:
synapse development and plasticityGoogle:
"Leigh Needleman"Mean distance: 13.85 (cluster 6) | S | N | B | C | P |
Parents
Sign in to add mentor| George W. Huntley | research assistant | 1998-2000 | Mount Sinai School of Medicine | |
| John Marshall | grad student | 2000-2006 | Brown | |
| (Regulation of kainate receptors at the synapse.) | ||||
| A. Kimberly McAllister | post-doc | 2007- | UC Davis | |
| Catherine Dulac | research scientist | 2011- | Harvard | |
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Publications
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| Perez JD, Rubinstein ND, Fernandez DE, et al. (2015) Quantitative and functional interrogation of parent-of-origin allelic expression biases in the brain. Elife. 4 |
| Needleman LA, McAllister AK. (2012) The major histocompatibility complex and autism spectrum disorder. Developmental Neurobiology. 72: 1288-301 |
| Glynn MW, Elmer BM, Garay PA, et al. (2011) MHCI negatively regulates synapse density during the establishment of cortical connections. Nature Neuroscience. 14: 442-51 |
| Needleman LA, Liu XB, El-Sabeawy F, et al. (2010) MHC class I molecules are present both pre- and postsynaptically in the visual cortex during postnatal development and in adulthood. Proceedings of the National Academy of Sciences of the United States of America. 107: 16999-7004 |
| Needleman LA, McAllister AK. (2008) Seeing the light: insulin receptors and the CNS. Neuron. 58: 653-5 |
| Salinas GD, Blair LA, Needleman LA, et al. (2006) Actinfilin is a Cul3 substrate adaptor, linking GluR6 kainate receptor subunits to the ubiquitin-proteasome pathway. The Journal of Biological Chemistry. 281: 40164-73 |
| Gao L, Blair LA, Salinas GD, et al. (2006) Insulin-like growth factor-1 modulation of CaV1.3 calcium channels depends on Ca2+ release from IP3-sensitive stores and calcium/calmodulin kinase II phosphorylation of the alpha1 subunit EF hand. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 6259-68 |
| Ren Z, Riley NJ, Needleman LA, et al. (2003) Cell surface expression of GluR5 kainate receptors is regulated by an endoplasmic reticulum retention signal. The Journal of Biological Chemistry. 278: 52700-9 |
| Poskanzer K, Needleman LA, Bozdagi O, et al. (2003) N-cadherin regulates ingrowth and laminar targeting of thalamocortical axons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 23: 2294-305 |
| Gil OD, Needleman L, Huntley GW. (2002) Developmental patterns of cadherin expression and localization in relation to compartmentalized thalamocortical terminations in rat barrel cortex. The Journal of Comparative Neurology. 453: 372-88 |